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Diabetes Discussion
Type 1 Diabetes
Really confused, test say I am no longer Type1.
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<blockquote data-quote="catapillar" data-source="post: 1223592" data-attributes="member: 32394"><p>I don't think doing an OGTT would really work to determine insulin resistance in someone diagnosed with type 1 - because if you don't bolus for the sugary drink (which you didn't and you're not supposed to) all your reaction during the OGTT will tell you is your reaction to sugar, rather than insulin.</p><p></p><p>Was the OGTT done at your GP surgery rather than at a diabetic clinic? I don't think an OGTT is usually recommended for type 1s so I wouldn't put much store in the results to be honest.</p><p></p><p>If there is a query over what type of diabetes you have you should be seeing an endocrinologist at the hospital.</p><p></p><p>There are a few tests they can do to look into things:</p><p></p><p>1. Cpeptide test - this will tell you if you are making any of your own insulin. If you are making your own insulin, that doesn't mean you aren't type 1 as a honeymooning type 1 will have residual insulin production.</p><p></p><p>2. Antibody tests - this is a test to see if you have GAD antibodies (and some others) which are associated with autoimmune type 1 diabetes. If it comes back GAD positive, you will definitely be type 1. But if it comes back negative it doesn't mean you aren't type 1, about 25% of type 1s are GAD negative</p><p></p><p>3. Genetic testing - on the NHS they usually won't run the genetic testing for MODY until you have a negative GAD test (because if you are GAD positive there is no point doing the expensive genetic testing because they will know that you are definitely type 1) so what I think they do is take the blood and samples all at once, send it all off to be tested and run the GAD test first, only if it comes back negative will they proceed to run the genetic tests on the samples.</p><p></p><p>Hope you get to speak to someone helpful when you have your tests done on Tuesday.</p></blockquote><p></p>
[QUOTE="catapillar, post: 1223592, member: 32394"] I don't think doing an OGTT would really work to determine insulin resistance in someone diagnosed with type 1 - because if you don't bolus for the sugary drink (which you didn't and you're not supposed to) all your reaction during the OGTT will tell you is your reaction to sugar, rather than insulin. Was the OGTT done at your GP surgery rather than at a diabetic clinic? I don't think an OGTT is usually recommended for type 1s so I wouldn't put much store in the results to be honest. If there is a query over what type of diabetes you have you should be seeing an endocrinologist at the hospital. There are a few tests they can do to look into things: 1. Cpeptide test - this will tell you if you are making any of your own insulin. If you are making your own insulin, that doesn't mean you aren't type 1 as a honeymooning type 1 will have residual insulin production. 2. Antibody tests - this is a test to see if you have GAD antibodies (and some others) which are associated with autoimmune type 1 diabetes. If it comes back GAD positive, you will definitely be type 1. But if it comes back negative it doesn't mean you aren't type 1, about 25% of type 1s are GAD negative 3. Genetic testing - on the NHS they usually won't run the genetic testing for MODY until you have a negative GAD test (because if you are GAD positive there is no point doing the expensive genetic testing because they will know that you are definitely type 1) so what I think they do is take the blood and samples all at once, send it all off to be tested and run the GAD test first, only if it comes back negative will they proceed to run the genetic tests on the samples. Hope you get to speak to someone helpful when you have your tests done on Tuesday. [/QUOTE]
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Really confused, test say I am no longer Type1.
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