Researchers have now discovered that very small amounts of insulin are produced in most patients and that levels in the blood often respond to food intake.
That is interesting Catherine. I know Phoenix has often posted links referring to the Joslin 50 who are found to be still producing some insulin after half a century of diabetes.
An interesting part of this article is:
"The development has been enabled by new technology that can measure very small concentrations of insulin in the blood"
I wonder if this might lead to more accurate meters?
Robert
Fascinating!
Does this mean T1 and T2 are less different than was thought?
I'll follow this with interest. I do think it makes Bernstein's method of control even more valid.
Hana
As well as the Joslin trials, the Faustman lab has also found residual insulin production.
Medscape reports this latest reseach in a little more detail. There is also a link to a zipped copy of the original paper.
Personally, I can't see that the test has any relevance to blood glucose testing but then again I have no understanding of the procedure ; it sounds very technical.
Ultrasensitive C-peptide ELISA (Mercodia, Sylveniusgatanm, Sweden), which is a solid-phase two-site enzyme immunoassay that uses a peroxidase-TMB (3,3′,5,5′-tetramethybenzidine) label on an automated ELISA system (Dynex DSX; Launch Diagnostics, Longfield, UK).
They found that this could also detect low-level insulin secretion . They liked it because it meant that they could use this test in further larger scale research. The subjects could just provide urine samples done at home.
I also wonder if this is a cheaper test, if so it could make c peptide testing more readily available.
this is really interesting and *could* indicate why some peoples blood sugars respond differently day-to-day I would have thought? could it be I'm producing just tiny amounts to knock things off balance?