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Research in Type 1 overturns idea of zero insulin.

  • Thread starter Thread starter catherinecherub
  • Start Date Start Date
That is interesting Catherine. I know Phoenix has often posted links referring to the Joslin 50 who are found to be still producing some insulin after half a century of diabetes.
 
An interesting part of this article is:
"The development has been enabled by new technology that can measure very small concentrations of insulin in the blood"
I wonder if this might lead to more accurate meters?
Robert
 
Fascinating!
Does this mean T1 and T2 are less different than was thought?
I'll follow this with interest. I do think it makes Bernstein's method of control even more valid.
Hana
 
As well as the Joslin trials, the Faustman lab has also found residual insulin production.
Medscape reports this latest reseach in a little more detail. There is also a link to a zipped copy of the original paper.

http://www.medscape.com/viewarticle/812405

Personally, I can't see that the test has any relevance to blood glucose testing but then again I have no understanding of the procedure ; it sounds very technical.
Ultrasensitive C-peptide ELISA (Mercodia, Sylveniusgatanm, Sweden), which is a solid-phase two-site enzyme immunoassay that uses a peroxidase-TMB (3,3′,5,5′-tetramethybenzidine) label on an automated ELISA system (Dynex DSX; Launch Diagnostics, Longfield, UK).
Click to expand...

What was interesting is that they also trialled another method for assessing c peptide.
urinary C-peptide:creatinine ratio (UCPCR) is a re- cently described method of assessing C-peptide production that involves using a spot urine test
Click to expand...
They found that this could also detect low-level insulin secretion . They liked it because it meant that they could use this test in further larger scale research. The subjects could just provide urine samples done at home.

I also wonder if this is a cheaper test, if so it could make c peptide testing more readily available.
 
this is really interesting and *could* indicate why some peoples blood sugars respond differently day-to-day I would have thought? could it be I'm producing just tiny amounts to knock things off balance?
 
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