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Reversing diabetes
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<blockquote data-quote="Biggles2" data-source="post: 1682695" data-attributes="member: 406880"><p>Agreed, and that goes to the crux of this argument [USER=219467]@bulkbiker[/USER]. Diabetes is such a heterogeneous disease. How it is expressed in different people will be different because each one of us has a different, unique physiology.</p><p></p><p>For example, our individual beta cell dysfunction will be different depending on a whole host of factors (length of disease, history of pancreatitis etc), and our level of insulin resistance may very well be expressed at different weights - think of individuals who are TOFI, or those ethnicities where a lower BMI is used to trigger diabetes screening because of their higher risk. </p><p></p><p>The number of carbs I need to consume to maintain my levels may be very different from the number of carbs another person needs to maintain the same levels. I marvel at those who can aim for 100gm carbs per day - my requirement to stay in goal is 30gm or under.</p><p></p><p>So, the pathophysiology matters. And we need clear definitions so that our individual risk factors for complications will always be front and center when we are receiving care, so that we don't fall through the cracks.</p></blockquote><p></p>
[QUOTE="Biggles2, post: 1682695, member: 406880"] Agreed, and that goes to the crux of this argument [USER=219467]@bulkbiker[/USER]. Diabetes is such a heterogeneous disease. How it is expressed in different people will be different because each one of us has a different, unique physiology. For example, our individual beta cell dysfunction will be different depending on a whole host of factors (length of disease, history of pancreatitis etc), and our level of insulin resistance may very well be expressed at different weights - think of individuals who are TOFI, or those ethnicities where a lower BMI is used to trigger diabetes screening because of their higher risk. The number of carbs I need to consume to maintain my levels may be very different from the number of carbs another person needs to maintain the same levels. I marvel at those who can aim for 100gm carbs per day - my requirement to stay in goal is 30gm or under. So, the pathophysiology matters. And we need clear definitions so that our individual risk factors for complications will always be front and center when we are receiving care, so that we don't fall through the cracks. [/QUOTE]
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