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<blockquote data-quote="TwoTone" data-source="post: 2338079" data-attributes="member: 516838"><p>Hi Dudette1. After 15 years of managing diabetes and being prescribed ever increasing doses of Metformin in an attempt to keep T2D under control, I stopped eating meat. After 2 3/4 years I've gone from 2000mg of Metformin to 500mg. All under the guidance of GP and regular A1c tests - am norm range, plus or minus. Connection? I'm leaning towards strong influence of uric acid levels caused by eating purines. Was diagnosed with gout 5 years before T2D diagnosis. A ver high proportion of T2Ds will suffer from gout (>70% and this is stated somewhere on this site). The highest levels of purines is in meat. Purines are metabolized in to uric acid in the body and normally passed when one pees. If it doesn't, it builds in the bloodstream.</p><p></p><p>So do a search on "uric acid insulin resistance" and you'll come across research connecting high uric acid with insulin resistance.</p><p></p><p>Into remission I think. Going back to where I was? I don't believe I want to go there! As someone on a forum once said "being diagnosed T2D was probably the best thing for you".</p><p></p><p>Good luck</p><p>Tony</p></blockquote><p></p>
[QUOTE="TwoTone, post: 2338079, member: 516838"] Hi Dudette1. After 15 years of managing diabetes and being prescribed ever increasing doses of Metformin in an attempt to keep T2D under control, I stopped eating meat. After 2 3/4 years I've gone from 2000mg of Metformin to 500mg. All under the guidance of GP and regular A1c tests - am norm range, plus or minus. Connection? I'm leaning towards strong influence of uric acid levels caused by eating purines. Was diagnosed with gout 5 years before T2D diagnosis. A ver high proportion of T2Ds will suffer from gout (>70% and this is stated somewhere on this site). The highest levels of purines is in meat. Purines are metabolized in to uric acid in the body and normally passed when one pees. If it doesn't, it builds in the bloodstream. So do a search on "uric acid insulin resistance" and you'll come across research connecting high uric acid with insulin resistance. Into remission I think. Going back to where I was? I don't believe I want to go there! As someone on a forum once said "being diagnosed T2D was probably the best thing for you". Good luck Tony [/QUOTE]
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