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<blockquote data-quote="Oldvatr" data-source="post: 1523496" data-attributes="member: 196898"><p>I think this is an oversimplification, and I cannot find any evidence that this is what happens.</p><p></p><p>I believe IR is linked to a fatty liver as in Metabolic Syndrome, and googling NAFLD reduction brings up a multitude of diets that people put forward for reducing a fatty liver, but I could not see WFPB mentioned at all. Most diets seem to be ketogenic, and employ fat burning technique to get the liver to empty its fat stores. For keto to happen, the blood glucose levels MUST be low, so it is inherent that a low carb and limited protein intake is needed. This process seems believable to me, and makes sense. </p><p></p><p>A low fat diet will only work if the fat is ultra low, almost negligible, and since the brain has to have some fat to operate and the body also needs it to manufacture cholesterol to transport the B vitamins etc, then what you propose is to starve the brain of essential lipids so that the liver empties to compensate. I don't think this would be very efficient at reducing a fatty liver, and sounds a bit worrying. But there was a study that showed that a high carb ultra low fat can be used to reduce diabetes, so maybe WFPB does reduce IR. Not convinced though, since fasting for long periods would have similar claim, and would also be a way of curing T2D. But evidence so far is that it does not do that on its own. Mind you, excessive fasting would work and cure all manner of diseases - permanently , but its a bit extreme - its called death by starvation.</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 1523496, member: 196898"] I think this is an oversimplification, and I cannot find any evidence that this is what happens. I believe IR is linked to a fatty liver as in Metabolic Syndrome, and googling NAFLD reduction brings up a multitude of diets that people put forward for reducing a fatty liver, but I could not see WFPB mentioned at all. Most diets seem to be ketogenic, and employ fat burning technique to get the liver to empty its fat stores. For keto to happen, the blood glucose levels MUST be low, so it is inherent that a low carb and limited protein intake is needed. This process seems believable to me, and makes sense. A low fat diet will only work if the fat is ultra low, almost negligible, and since the brain has to have some fat to operate and the body also needs it to manufacture cholesterol to transport the B vitamins etc, then what you propose is to starve the brain of essential lipids so that the liver empties to compensate. I don't think this would be very efficient at reducing a fatty liver, and sounds a bit worrying. But there was a study that showed that a high carb ultra low fat can be used to reduce diabetes, so maybe WFPB does reduce IR. Not convinced though, since fasting for long periods would have similar claim, and would also be a way of curing T2D. But evidence so far is that it does not do that on its own. Mind you, excessive fasting would work and cure all manner of diseases - permanently , but its a bit extreme - its called death by starvation. [/QUOTE]
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