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Rising BS levels but don’t know why
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<blockquote data-quote="JohnEGreen" data-source="post: 1789192" data-attributes="member: 223921"><p>I know this is a fairly old thread but have recently learned that prednisolone can have a marked affect on blood sugars this is because it reduces or hinders the livers sensitivity to insulin , insulin produced by the pancreas should trigger the liver into lessening its production of sugars or even stop it altogether but preds can cause the liver not to be triggered and it will just carry on producing sugars thus causing high blood sugar levels and an increase in IR. A complication of this is that it is not constant and the affect can vary and at times disappear for periods the liver then recieves the message to cut down or stop producing sugars and can cause unpredictable hypos this is an unfortunate complication of prednisolone induced or Type 3E diabetes.</p><p></p><p>As I am now only just coming to understand.</p><p></p><p>This can also be a problem for T1's or insulin dependent T2's as the prednisolone acts in the same manner on insulin that has been produced by the pancreas or injected insulin. If they are given Prednisolone therapy.</p></blockquote><p></p>
[QUOTE="JohnEGreen, post: 1789192, member: 223921"] I know this is a fairly old thread but have recently learned that prednisolone can have a marked affect on blood sugars this is because it reduces or hinders the livers sensitivity to insulin , insulin produced by the pancreas should trigger the liver into lessening its production of sugars or even stop it altogether but preds can cause the liver not to be triggered and it will just carry on producing sugars thus causing high blood sugar levels and an increase in IR. A complication of this is that it is not constant and the affect can vary and at times disappear for periods the liver then recieves the message to cut down or stop producing sugars and can cause unpredictable hypos this is an unfortunate complication of prednisolone induced or Type 3E diabetes. As I am now only just coming to understand. This can also be a problem for T1's or insulin dependent T2's as the prednisolone acts in the same manner on insulin that has been produced by the pancreas or injected insulin. If they are given Prednisolone therapy. [/QUOTE]
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