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Message: <blockquote data-quote="BarbaraG" data-source="post: 1453307" data-attributes="member: 47277">My hunch is that both the test instructions AND the "normal" levels are for people who eat a standard, i.e. high carb, diet.Long term low carbers who are not diabetic often find their fasting BG goes up, and they get worried about it. The explanation is physiological insulin resistance, aka adaptive glucose sparing. When you're not supplying your body carbs all the time, it saves them for the tissues which have to have glucose. This manifests as reduced insulin sensitivity in muscles, but is completely different from the insulin resistance underlying T2D, where the liver is the main culprit.I speculate that if OGTT's were done on people who have always had normal insulin sensitivity but who eat low carb, there would be a different set of values recognised as normal.  If you would never normally eat anything like 75g glucose in a whole day, the fact that you spike massively when they force you to drink it in one go is neither here nor there.</blockquote>

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