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Serious problem with paracetamol
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<blockquote data-quote="Dark Horse" data-source="post: 1318932" data-attributes="member: 52527"><p>In your original post, you said that you'd taken 3 x 500 mg tablet which is why I warned about taking more than 1000 mg. However, in this post you say you don't take more than 1000 mg - I assume the original was a typo (easily done)?</p><p></p><p>The amount of paracetamol in all genuine UK tablets etc. is very strictly controlled and will not be the cause of your problem. </p><p></p><p>Your problem could be caused by any of the following:-</p><ol> <li data-xf-list-type="ol">Different brands of paracetamol can have different non-active ingredients and these could theoretically affect the rate of absorption in some individuals. In which case, trying a more easily absorbed brand might help, e.g. <a href="http://www.boots.com/en/Panadol-Advance-500-mg-Tablets-32-_872998/" target="_blank">http://www.boots.com/en/Panadol-Advance-500-mg-Tablets-32-_872998/</a></li> <li data-xf-list-type="ol">You might have unfortunately been sold counterfeit paracetamol with no active ingredient. Counterfeit tablets are thought to make up about 1% of drug sales in developed countries. They tend to be harder than genuine tablets and packets may contain spelling errors. <a href="http://www.science20.com/news_releases/simple_test_to_detect_fake_medicines" target="_blank">http://www.science20.com/news_releases/simple_test_to_detect_fake_medicines</a></li> <li data-xf-list-type="ol">You have changed in some way since you last took Depon and would therefore have problems even if you did manage to get some more of it. Fore example, developing gastroparesis or eating a high fat diet could delay stomach emptying and therefore absorption. Taking an easily absorbed paracetamol on an empty stomach might help.</li> </ol><p>By the way, paracetamol is an analgesic but is not not a NSAID (non-steroidal anti-inflammatory). It has very little anti-inflammatory activity.</p></blockquote><p></p>
[QUOTE="Dark Horse, post: 1318932, member: 52527"] In your original post, you said that you'd taken 3 x 500 mg tablet which is why I warned about taking more than 1000 mg. However, in this post you say you don't take more than 1000 mg - I assume the original was a typo (easily done)? The amount of paracetamol in all genuine UK tablets etc. is very strictly controlled and will not be the cause of your problem. Your problem could be caused by any of the following:- [LIST=1] [*]Different brands of paracetamol can have different non-active ingredients and these could theoretically affect the rate of absorption in some individuals. In which case, trying a more easily absorbed brand might help, e.g. [URL]http://www.boots.com/en/Panadol-Advance-500-mg-Tablets-32-_872998/[/URL] [*]You might have unfortunately been sold counterfeit paracetamol with no active ingredient. Counterfeit tablets are thought to make up about 1% of drug sales in developed countries. They tend to be harder than genuine tablets and packets may contain spelling errors. [URL]http://www.science20.com/news_releases/simple_test_to_detect_fake_medicines[/URL] [*]You have changed in some way since you last took Depon and would therefore have problems even if you did manage to get some more of it. Fore example, developing gastroparesis or eating a high fat diet could delay stomach emptying and therefore absorption. Taking an easily absorbed paracetamol on an empty stomach might help. [/LIST] By the way, paracetamol is an analgesic but is not not a NSAID (non-steroidal anti-inflammatory). It has very little anti-inflammatory activity. [/QUOTE]
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