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SICKLE CELL TRAIT.

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phillipweare

Newbie
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1
Type of diabetes
Type 2
Can anyone tell me how diskless TRAIT affects type 2 diabetes, and whitch is the correct blood test for results,I am on 4 gliclazide and 4 slow acting metfomin a day .do I need a Hbac1,or a fructosamin test for correct results .my blood singers stay around 114 to 16 ,and my last hbac1 was 135
thanks in advance
Phillip
 
The HbA1c test is predicated on blood cells surviving 100-120 days.

In full sickle cell anaemia there is a change in one of the amino acids in haemoglobin causing it to fold differently and change
the shape of the cell.

These cells have a shorter life - this will affect the length of time available for glucose to stick to it

In sickle cell TRAIT there is only one copy of the changed template, and there only a reduced number of sicke cells.

( It is thought that sickle cell trait has provided some evolutionary advantage against malaria - as the parasite does not breed in damaged cells )
 
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