Search
Search titles only
By:
Search titles only
By:
Home
Forums
New posts
Search forums
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
Search
Search titles only
By:
Search titles only
By:
New posts
Search forums
Menu
Install the app
Install
Reply to Thread
Guest, we'd love to know what you think about the forum! Take the
Diabetes Forum Survey 2024 »
Home
Forums
Diabetes Discussion
Newly Diagnosed
Statins & high cholesterol
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Message
<blockquote data-quote="TheBigNewt" data-source="post: 1664141" data-attributes="member: 380756"><p>Simvistatin (aka Zocor) came out before atorvastatin (Lipitor) and at the time was more potent than the original statin (lovastatin) and the 2nd one (pravastatin). Muscle pain from statins is the most common side effect and stops when the drug is stopped (within a few weeks usually). The statin that is the most chemically different is pravastatin, which is also the least potent. Lipitor is the most potent generic, max dose is 80mg, and by far the best studied in patients with CAD. Crestor (rosuvastatin) is newest and now the most potent at 40mg, not yet generic.</p><p> You're talking about primary prevention of CAD which is much harder to prove than secondary prevention. If you have established CAD, usually after an "event" (heart attack, stent, bypass) then it's like having cancer, your future cause of death has most likely been established and you'd be wise to take the only drug class proven to alter that course other than aspirin. I'm not talking about someone found to have a minor 50% blockage in one vessel. A lot of Type 2's have not so great lipids as well, which is why may are prescribed statins in addition to hypoglycemics (metformin, insulin, etc.). That combination not infrequently lead to a CAD event. Type 1 diabetics are a different animal, tend to get "microvascular" disease (eyes, kidneys) and I don't think have been studied with statins probably because they tend to be much younger and there are far fewer of them around.</p></blockquote><p></p>
[QUOTE="TheBigNewt, post: 1664141, member: 380756"] Simvistatin (aka Zocor) came out before atorvastatin (Lipitor) and at the time was more potent than the original statin (lovastatin) and the 2nd one (pravastatin). Muscle pain from statins is the most common side effect and stops when the drug is stopped (within a few weeks usually). The statin that is the most chemically different is pravastatin, which is also the least potent. Lipitor is the most potent generic, max dose is 80mg, and by far the best studied in patients with CAD. Crestor (rosuvastatin) is newest and now the most potent at 40mg, not yet generic. You're talking about primary prevention of CAD which is much harder to prove than secondary prevention. If you have established CAD, usually after an "event" (heart attack, stent, bypass) then it's like having cancer, your future cause of death has most likely been established and you'd be wise to take the only drug class proven to alter that course other than aspirin. I'm not talking about someone found to have a minor 50% blockage in one vessel. A lot of Type 2's have not so great lipids as well, which is why may are prescribed statins in addition to hypoglycemics (metformin, insulin, etc.). That combination not infrequently lead to a CAD event. Type 1 diabetics are a different animal, tend to get "microvascular" disease (eyes, kidneys) and I don't think have been studied with statins probably because they tend to be much younger and there are far fewer of them around. [/QUOTE]
Verification
Post Reply
Home
Forums
Diabetes Discussion
Newly Diagnosed
Statins & high cholesterol
Top
Bottom
Find support, ask questions and share your experiences. Ad free.
Join the community »
This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies.
Accept
Learn More.…