Search
Search titles only
By:
Search titles only
By:
Home
Forums
New posts
Search forums
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
Search
Search titles only
By:
Search titles only
By:
New posts
Search forums
Menu
Install the app
Install
Reply to Thread
Guest, we'd love to know what you think about the forum! Take the
Diabetes Forum Survey 2024 »
Home
Forums
Diabetes Discussion
Newly Diagnosed
Steroid-induced diabetes - permanent or temporary?
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Message
<blockquote data-quote="JonB100" data-source="post: 2203875" data-attributes="member: 496681"><p>Taks I had a liver transplant nine years ago, for PSC, an autoimmune condition. As you know a consequence of taking strong long term anti rejection drugs such as Tacrolimus, is a number of other unfortunate health conditions.</p><p></p><p>Two years ago I was diagnosed as diabetic and put directly on insulin, Humilin I twice daily. PTDM is unusual but more common soon after transplant. After transplant my colitis, a feature of my liver condition, became very active, hence the use of prednisolone and consequential secondary adrenal insufficiency.</p><p></p><p>Often folks on long term corticosteroids suffer from high blood glucose levels, and this could be a related explanation of my eventual diabetes. But other than perhaps many years ago my steriod use has been well managed and I don't think this explains my current diagnosis.</p><p></p><p>Three years ago I luckily caught PTLD in it's infancy, Burkitts lymphona, an extremely aggressive cancer. By chance this was identified while undertaking an experimental voluntary colonoscopy. Otherwise I wouldn't be here typing this. I strongly suspect, or hope, that my diabetes was a consequence of the drug regime experienced to eradicate this B cell cancer, Rituximab.</p><p></p><p>Only in the last week have a realised that my diabetes has been confounded by my hydrocortisone use. For six years I've taken this drug twice daily, in the hope of completely weaning off it. This has meant frequent morning hypoglycaemic events. </p><p></p><p>So now I'm splitting my cortisol three ways, taking a first 10mg dose at 6 a.m. I'm taking blood glucose readings every waking two hours. I can see the morning gluconeogenesis process raising my levels before breakfast. I'm now dropping my insulin slowly by two units per week, today at 12 units once a day.</p><p></p><p>I'm hoping to eventually be insulin free and to have resolved my diabetes.</p><p></p><p>Strange how optimistic I am, - we will see.</p></blockquote><p></p>
[QUOTE="JonB100, post: 2203875, member: 496681"] Taks I had a liver transplant nine years ago, for PSC, an autoimmune condition. As you know a consequence of taking strong long term anti rejection drugs such as Tacrolimus, is a number of other unfortunate health conditions. Two years ago I was diagnosed as diabetic and put directly on insulin, Humilin I twice daily. PTDM is unusual but more common soon after transplant. After transplant my colitis, a feature of my liver condition, became very active, hence the use of prednisolone and consequential secondary adrenal insufficiency. Often folks on long term corticosteroids suffer from high blood glucose levels, and this could be a related explanation of my eventual diabetes. But other than perhaps many years ago my steriod use has been well managed and I don't think this explains my current diagnosis. Three years ago I luckily caught PTLD in it's infancy, Burkitts lymphona, an extremely aggressive cancer. By chance this was identified while undertaking an experimental voluntary colonoscopy. Otherwise I wouldn't be here typing this. I strongly suspect, or hope, that my diabetes was a consequence of the drug regime experienced to eradicate this B cell cancer, Rituximab. Only in the last week have a realised that my diabetes has been confounded by my hydrocortisone use. For six years I've taken this drug twice daily, in the hope of completely weaning off it. This has meant frequent morning hypoglycaemic events. So now I'm splitting my cortisol three ways, taking a first 10mg dose at 6 a.m. I'm taking blood glucose readings every waking two hours. I can see the morning gluconeogenesis process raising my levels before breakfast. I'm now dropping my insulin slowly by two units per week, today at 12 units once a day. I'm hoping to eventually be insulin free and to have resolved my diabetes. Strange how optimistic I am, - we will see. [/QUOTE]
Verification
Post Reply
Home
Forums
Diabetes Discussion
Newly Diagnosed
Steroid-induced diabetes - permanent or temporary?
Top
Bottom
Find support, ask questions and share your experiences. Ad free.
Join the community »
This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies.
Accept
Learn More.…