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Steroid-induced diabetes - permanent or temporary?
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<blockquote data-quote="Tophat1900" data-source="post: 2224479" data-attributes="member: 362123"><p>Hello, </p><p></p><p>I'm a double lung transplant recipient. So, steriods are part of that treatment along with Tacro. Tacrolimus inhibits insulin secretion on it's own, and we all know what prednisone does to bg levels, it impairs beta cell function. I'm on 7mg a day, I take levimer and split the dose. </p><p></p><p>My transplant was in 1997, so have been on pred ever since. I have been on insulin for the last 3 years, the drugs just basically wear down the production of insulin over time. And I do low carb/keto to do my best to manage it.... and that may well of prolonged the introduction of insulin. Everyone at the lung transplant clinic I attend is diabetic. I should point out I have no idea what their diet is like. This does play an important part in the development of steriod induced diabetes. </p><p></p><p>The dietician is a believer in continuing to eat the same foods as before that certainly contributed to the development of diabetes. Believes sweet potatoes and wholegrain bread is perfectly healthy and a good choice. I think this is absolute rubbish. If your pancreas is having a hard time with the drugs then it makes no sense to be provoking it further with foods that require a lot of insulin. The other thing is if you are a TOFI of not, this I think is important. It is much harder for a TOFI to deal with high carb stuff like bread for example then it is for someone who can store a lot of fat. The work load on the pancreas is just greater and imo you can become a diabetic much quicker. </p><p></p><p>The anti-rejection medications increase the risk of heart disease, and prednisone really elevates the risk. This info has most likely been collected from people taking these meds and following the SAD (standard awefull diet). Which I think makes diet and avoiding all the high carb foods and rubbish really important. Just my thoughts on it.</p></blockquote><p></p>
[QUOTE="Tophat1900, post: 2224479, member: 362123"] Hello, I'm a double lung transplant recipient. So, steriods are part of that treatment along with Tacro. Tacrolimus inhibits insulin secretion on it's own, and we all know what prednisone does to bg levels, it impairs beta cell function. I'm on 7mg a day, I take levimer and split the dose. My transplant was in 1997, so have been on pred ever since. I have been on insulin for the last 3 years, the drugs just basically wear down the production of insulin over time. And I do low carb/keto to do my best to manage it.... and that may well of prolonged the introduction of insulin. Everyone at the lung transplant clinic I attend is diabetic. I should point out I have no idea what their diet is like. This does play an important part in the development of steriod induced diabetes. The dietician is a believer in continuing to eat the same foods as before that certainly contributed to the development of diabetes. Believes sweet potatoes and wholegrain bread is perfectly healthy and a good choice. I think this is absolute rubbish. If your pancreas is having a hard time with the drugs then it makes no sense to be provoking it further with foods that require a lot of insulin. The other thing is if you are a TOFI of not, this I think is important. It is much harder for a TOFI to deal with high carb stuff like bread for example then it is for someone who can store a lot of fat. The work load on the pancreas is just greater and imo you can become a diabetic much quicker. The anti-rejection medications increase the risk of heart disease, and prednisone really elevates the risk. This info has most likely been collected from people taking these meds and following the SAD (standard awefull diet). Which I think makes diet and avoiding all the high carb foods and rubbish really important. Just my thoughts on it. [/QUOTE]
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