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Message: <blockquote data-quote="Melgar" data-source="post: 2764092" data-attributes="member: 520626">[USER=598725]@Button43[/USER] Food choices have been the most significant means of reducing my IBS.  I can see why a very low carb diet can work. Gluten was the most significant trigger for my IBS and since stopping foods containing any gluten my episodes have dramatically decreased. Significantly reducing FODMAPs, and taking probiotics daily, have been extremely positive for me.Specifically, I wondered whether Metformin disrupts the intestinal bacteria in the gut. There have been studies on Metformin and the microbiome which suggest it does, other studies show that Metformin's effect on the gut inconclusive. I take my probiotics. Probiotic yoghurt works just as well, but that can, at times, give me mild IBS, likely the lactose !I have attached a study. It's a but technical as all these studies tend to be.<a href="https://diabetesjournals.org/care/article/44/7/1462/138809/Metformin-Affects-Gut-Microbiome-Composition-and" target="_blank">https://diabetesjournals.org/care/article/44/7/1462/138809/Metformin-Affects-Gut-Microbiome-Composition-and</a>ed spelling</blockquote>

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