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T1 CURE...????? really
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<blockquote data-quote="phoenix" data-source="post: 780613" data-attributes="member: 12578"><p>You may be be wrong about having no working insulin producing cells. Beta cells are not all destroyed at the time of diagnosis. Some people have residual production when they have had T1 for over 50 years. This isn't the case for all after 40+ years. It does though seem that at diagnosis people still have some functional insulin production and that the loss of this residual function is far slower than was thought in the past.</p><p>It is also suggests that some new cells are created but unfortunately die because of the autoimmune process during this period .</p><p></p><p> </p><p>Note that as well as finding c pep in the majority of living T1s in this study they also found histological evidence of at least a few insulin positive cells in nine pancreases examined post mortem. (some had very few but a couple far more so it does seem to be variable)</p><p>Residual Insulin Production and Pancreatic-CellTurnover After 50 Years of Diabetes: Joslin Medalist Study <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963543/#!po=34.2105" target="_blank">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963543/#!po=34.2105</a></p><p> Dr Faustman has also shown evidence of the persitence of dectable c peptide production.</p><p><a href="http://www.healthline.com/diabetesmine/faustman-research-update-beta-cell-function-persists-in-long-time-type-1-pwds#1" target="_blank">http://www.healthline.com/diabetesmine/faustman-research-update-beta-cell-function-persists-in-long-time-type-1-pwds#1</a></p><p>The paper mentioned is here <a href="http://care.diabetesjournals.org/content/35/3/465.full" target="_blank">http://care.diabetesjournals.org/content/35/3/465.full</a></p><p></p><p>As for stem cells, The cells used in this promising research are <a href="http://en.wikipedia.org/wiki/Blastocyst" target="_blank">blastocysts</a> 'left over' from in vitro fertilisation.</p><p><a href="http://medwatch.dk/Top_picks_in_english/article4344670.ece" target="_blank">http://medwatch.dk/Top_picks_in_english/article4344670.ece</a></p></blockquote><p></p>
[QUOTE="phoenix, post: 780613, member: 12578"] You may be be wrong about having no working insulin producing cells. Beta cells are not all destroyed at the time of diagnosis. Some people have residual production when they have had T1 for over 50 years. This isn't the case for all after 40+ years. It does though seem that at diagnosis people still have some functional insulin production and that the loss of this residual function is far slower than was thought in the past. It is also suggests that some new cells are created but unfortunately die because of the autoimmune process during this period . Note that as well as finding c pep in the majority of living T1s in this study they also found histological evidence of at least a few insulin positive cells in nine pancreases examined post mortem. (some had very few but a couple far more so it does seem to be variable) Residual Insulin Production and Pancreatic-CellTurnover After 50 Years of Diabetes: Joslin Medalist Study [URL]http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963543/#!po=34.2105[/URL] Dr Faustman has also shown evidence of the persitence of dectable c peptide production. [URL]http://www.healthline.com/diabetesmine/faustman-research-update-beta-cell-function-persists-in-long-time-type-1-pwds#1[/URL] The paper mentioned is here [URL]http://care.diabetesjournals.org/content/35/3/465.full[/URL] As for stem cells, The cells used in this promising research are [URL='http://en.wikipedia.org/wiki/Blastocyst']blastocysts[/URL] 'left over' from in vitro fertilisation. [URL]http://medwatch.dk/Top_picks_in_english/article4344670.ece[/URL] [/QUOTE]
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