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Type 1 Diabetes
T1 CURE...????? really
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<blockquote data-quote="rfmiles" data-source="post: 784491" data-attributes="member: 43718"><p>I've read of ONE verified cure of t1, probably the only one so far.</p><p>However, it had enough side effects that few of you will want to</p><p>try that method. Someone had an immune system problem that</p><p>was expected to kill him in perhaps a year, and also t1. The best</p><p>treatment available for that immune system condition was to kill</p><p>all the bone marrow with radiation, then perform a bone marrow</p><p>transplant, leaving the patient alive but requiring anti-rejection</p><p>medicines for the rest of his life. His doctors were able to find a</p><p>bone marrow donor with a small genetic difference that prevented</p><p>producing the type of white blood cells that attack the beta cells</p><p>of the pancreas. He had enough pancreas stem cells that he was</p><p>then able to regenerate enough beta cells for a cure.</p><p></p><p>Most of the other people offering a cure or reversal for diabetes</p><p>forget to mention that their definition of "cure" and/or "reversal"</p><p>does not match the definition used by the rest of the English-speaking</p><p>world.</p><p></p><p></p><p>Gene therapy by injecting viruses designed to insert a new gene</p><p>section is already in use occasionally, but with a major problem -</p><p>there is no control of where the new section is inserted into the</p><p>old genes, and if some cell gets it in the middle of a section that</p><p>prevents cancer in that type of cell, the patient has a significant</p><p>risk of developing cancer about ten years later. Leukemia in the</p><p>patient I've read about, but animal tests indicate that several other</p><p>types of cancer are also possible.</p><p></p><p></p><p>A Dr. Faustman is trying to develop to treatment to stop white</p><p>blood cell attacks on the beta cells, by using the BCG vaccine to</p><p>keep those white blood cells busy doing something else. The phase</p><p>1 trial included only 3 people with t1. One was able to stop taking</p><p>insulin for a few months, and another was able to reduce the amount</p><p>of insulin used. This suggests that some, but not all, of the people</p><p>with t1 still have enough stem cells in their pancreas to regenerate</p><p>the beta cells if the immune system stops attacking them. Note that</p><p>this was tried on too few people with t1 to say much on what</p><p>percentage it will help, though.</p><p></p><p><a href="http://www.faustmanlab.org/" target="_blank">http://www.faustmanlab.org/</a></p><p></p><p></p><p>A recent article on a new possibility:</p><p></p><p><<a href="http://www.monacowealthmanagement.com/articles/awareness/2015/20150203-awareness-breakthrough-pill-can-cure-diabetes.php>" target="_blank">http://www.monacowealthmanagement.com/articles/awareness/2015/20150203-awareness-breakthrough-pill-can-cure-diabetes.php></a></p><p></p><p>It involves controlling diabetes by daily use of a pill that contains</p><p>probiotics designed to produce insulin in the upper intestine. Tried</p><p>only on rats so far. At least one reporter has been seen describing</p><p>this as a cure for both t1 and t2, though.</p><p></p><p>I expect the major drug companies to work on such a cure only AFTER</p><p>at least one small drug company starts making money offering such a</p><p>cure, and the small drug companies to start offering one only after some</p><p>independent researcher does most of the work to develop such a cure.</p></blockquote><p></p>
[QUOTE="rfmiles, post: 784491, member: 43718"] I've read of ONE verified cure of t1, probably the only one so far. However, it had enough side effects that few of you will want to try that method. Someone had an immune system problem that was expected to kill him in perhaps a year, and also t1. The best treatment available for that immune system condition was to kill all the bone marrow with radiation, then perform a bone marrow transplant, leaving the patient alive but requiring anti-rejection medicines for the rest of his life. His doctors were able to find a bone marrow donor with a small genetic difference that prevented producing the type of white blood cells that attack the beta cells of the pancreas. He had enough pancreas stem cells that he was then able to regenerate enough beta cells for a cure. Most of the other people offering a cure or reversal for diabetes forget to mention that their definition of "cure" and/or "reversal" does not match the definition used by the rest of the English-speaking world. Gene therapy by injecting viruses designed to insert a new gene section is already in use occasionally, but with a major problem - there is no control of where the new section is inserted into the old genes, and if some cell gets it in the middle of a section that prevents cancer in that type of cell, the patient has a significant risk of developing cancer about ten years later. Leukemia in the patient I've read about, but animal tests indicate that several other types of cancer are also possible. A Dr. Faustman is trying to develop to treatment to stop white blood cell attacks on the beta cells, by using the BCG vaccine to keep those white blood cells busy doing something else. The phase 1 trial included only 3 people with t1. One was able to stop taking insulin for a few months, and another was able to reduce the amount of insulin used. This suggests that some, but not all, of the people with t1 still have enough stem cells in their pancreas to regenerate the beta cells if the immune system stops attacking them. Note that this was tried on too few people with t1 to say much on what percentage it will help, though. [URL]http://www.faustmanlab.org/[/URL] A recent article on a new possibility: <[URL]http://www.monacowealthmanagement.com/articles/awareness/2015/20150203-awareness-breakthrough-pill-can-cure-diabetes.php>[/URL] It involves controlling diabetes by daily use of a pill that contains probiotics designed to produce insulin in the upper intestine. Tried only on rats so far. At least one reporter has been seen describing this as a cure for both t1 and t2, though. I expect the major drug companies to work on such a cure only AFTER at least one small drug company starts making money offering such a cure, and the small drug companies to start offering one only after some independent researcher does most of the work to develop such a cure. [/QUOTE]
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