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The Fallacy of Average: How Using HbA1c Alone to Assess Glycemic Control Can Be Misleading
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<blockquote data-quote="Bluetit1802" data-source="post: 1590384" data-attributes="member: 94045"><p>Yes, I have read it. I am a little sceptical because they are based very old studies from the 1980s, and I'm not sure about their conclusion that glycation is reversible, and that earlier haemoglobin from the first part of the 2 to 3 month period has "lost" its glycation. This research was done in a test tube. Maybe it is different when the blood is still in the human body? </p><p></p><p>As the HbA1c is a very important tool in diagnosing diabetes and also monitoring control, I cannot understand why this research has not been taken on board by the powers that be, and why every one of the powers that be continue to believe that red blood cell survival times are so significant. However, I am willing to learn. Whatever, it is clear that the HbA1c is not as reliable as our doctors seem to think it is.</p><p></p><p><a href="http://www.diabetes.co.uk/forum/threads/scientists-question-accuracy-of-hba1c-testing-due-to-red-blood-cell-age-variability.110793/" target="_blank">http://www.diabetes.co.uk/forum/threads/scientists-question-accuracy-of-hba1c-testing-due-to-red-blood-cell-age-variability.110793/</a></p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581997/" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581997/</a></p><p></p><p><a href="https://patient.info/doctor/glycated-haemoglobin-hba1c" target="_blank">https://patient.info/doctor/glycated-haemoglobin-hba1c</a></p><p></p><p><a href="http://care.diabetesjournals.org/content/40/8/994" target="_blank">http://care.diabetesjournals.org/content/40/8/994</a></p><p></p><p><a href="http://www.gpnotebook.co.uk/simplepage.cfm?ID=x20070614192625295600&linkID=70250&cook=yes" target="_blank">http://www.gpnotebook.co.uk/simplepage.cfm?ID=x20070614192625295600&linkID=70250&cook=yes</a></p><p></p><p><a href="https://pbs.twimg.com/media/DG4FKXNUQAA2rMo.jpg" target="_blank">https://pbs.twimg.com/media/DG4FKXNUQAA2rMo.jpg</a></p></blockquote><p></p>
[QUOTE="Bluetit1802, post: 1590384, member: 94045"] Yes, I have read it. I am a little sceptical because they are based very old studies from the 1980s, and I'm not sure about their conclusion that glycation is reversible, and that earlier haemoglobin from the first part of the 2 to 3 month period has "lost" its glycation. This research was done in a test tube. Maybe it is different when the blood is still in the human body? As the HbA1c is a very important tool in diagnosing diabetes and also monitoring control, I cannot understand why this research has not been taken on board by the powers that be, and why every one of the powers that be continue to believe that red blood cell survival times are so significant. However, I am willing to learn. Whatever, it is clear that the HbA1c is not as reliable as our doctors seem to think it is. [URL]http://www.diabetes.co.uk/forum/threads/scientists-question-accuracy-of-hba1c-testing-due-to-red-blood-cell-age-variability.110793/[/URL] [URL]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581997/[/URL] [URL]https://patient.info/doctor/glycated-haemoglobin-hba1c[/URL] [URL]http://care.diabetesjournals.org/content/40/8/994[/URL] [URL]http://www.gpnotebook.co.uk/simplepage.cfm?ID=x20070614192625295600&linkID=70250&cook=yes[/URL] [URL]https://pbs.twimg.com/media/DG4FKXNUQAA2rMo.jpg[/URL] [/QUOTE]
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