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The Patterns in Which Diabetes Develops
- Thread starter daisy222
- Start Date
daisy222
Well-Known Member
I wish I known this earlier
By FBS 1 years ago was 5.7 and I was told it was normal and nothing to worry about...I was diagnosed back in May with FBS 7.1 and 8.5
"A 2007 Study Confirms Progression Within 3 Years to Diabetes with Fasting blood sugar over 100 mg/dl (5.6 mmol/L)
This was a study of 5,452 members of an HMO with no prior history of diabetes. You can read the full text here:
Progression From Newly Acquired Impaired Fasting Glusose to Type 2 Diabetes Gregory A. Nichols et al Diabetes Care. 2007; 30(2):228-33
This study found that,
Overall, 8.1% of subjects whose initial abnormal fasting glucose was 100-109 mg/dl (added IFG [impaired fasting glucose] subjects) and 24.3% of subjects whose initial abnormal fasting glucose was 110-125 mg/dl (original IFG subjects) developed diabetes (P < 0.0001).
Added IFG subjects who progressed to diabetes did so within a mean of 41.4 months, a rate of 1.34% per year. Original IFG subjects converted at a rate of 5.56% per year after an average of 29.0 months.
A steeper rate of increasing fasting glucose; higher BMI, blood pressure, and triglycerides; and lower HDL cholesterol predicted diabetes development. [emphasis mine]
What this means is that if your blood sugar tests over 100 mg/dl fasting more than once, your fasting blood sugar is likely to go over the 125 mg/dl (7.0 mmol/L) level used to diagnose full diabetes within 3 years.
More importantly, and not addressed in this article, if your blood sugar is at 100 mg/dl fasting, it is very likely that your post-meal blood sugar is heading towards the diabetic range, which is over 200 mg/dl (11.1 mmol/L) which is why your fasting blood sugar is deteriorating.
High post-meal blood sugars kill beta cells. If you can bring down those post-meal highs, you may be able to prevent the beta cell death that is destroying your fasting control!
Truly Normal is Clearly Lower than American Diabetes Association "Normal"
The data here suggest strongly that truly normal people--people whose fasting blood sugar is close to 82 mg/dl and whose 2-h result on an OGTT is closer to 90 than 140 probably don't become diabetic. Those whose blood sugars are higher than this true "normal" do even though the current diagnostic standard embraced by the American Diabetes Association tells them they are normal. They may go on for many years showing only slight changes from year to year, but eventually they suddenly hit a critical point where their blood sugar control suddenly deteriorates very swiftly."
By FBS 1 years ago was 5.7 and I was told it was normal and nothing to worry about...I was diagnosed back in May with FBS 7.1 and 8.5"A 2007 Study Confirms Progression Within 3 Years to Diabetes with Fasting blood sugar over 100 mg/dl (5.6 mmol/L)
This was a study of 5,452 members of an HMO with no prior history of diabetes. You can read the full text here:
Progression From Newly Acquired Impaired Fasting Glusose to Type 2 Diabetes Gregory A. Nichols et al Diabetes Care. 2007; 30(2):228-33
This study found that,
Overall, 8.1% of subjects whose initial abnormal fasting glucose was 100-109 mg/dl (added IFG [impaired fasting glucose] subjects) and 24.3% of subjects whose initial abnormal fasting glucose was 110-125 mg/dl (original IFG subjects) developed diabetes (P < 0.0001).
Added IFG subjects who progressed to diabetes did so within a mean of 41.4 months, a rate of 1.34% per year. Original IFG subjects converted at a rate of 5.56% per year after an average of 29.0 months.
A steeper rate of increasing fasting glucose; higher BMI, blood pressure, and triglycerides; and lower HDL cholesterol predicted diabetes development. [emphasis mine]
What this means is that if your blood sugar tests over 100 mg/dl fasting more than once, your fasting blood sugar is likely to go over the 125 mg/dl (7.0 mmol/L) level used to diagnose full diabetes within 3 years.
More importantly, and not addressed in this article, if your blood sugar is at 100 mg/dl fasting, it is very likely that your post-meal blood sugar is heading towards the diabetic range, which is over 200 mg/dl (11.1 mmol/L) which is why your fasting blood sugar is deteriorating.
High post-meal blood sugars kill beta cells. If you can bring down those post-meal highs, you may be able to prevent the beta cell death that is destroying your fasting control!
Truly Normal is Clearly Lower than American Diabetes Association "Normal"
The data here suggest strongly that truly normal people--people whose fasting blood sugar is close to 82 mg/dl and whose 2-h result on an OGTT is closer to 90 than 140 probably don't become diabetic. Those whose blood sugars are higher than this true "normal" do even though the current diagnostic standard embraced by the American Diabetes Association tells them they are normal. They may go on for many years showing only slight changes from year to year, but eventually they suddenly hit a critical point where their blood sugar control suddenly deteriorates very swiftly."
