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The presence of A1C heavily has an effect on transfusion of insulin in the blood

HICHAM_T2

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Hi

The question is in the subject title

The presence of A1C heavily has an effect on transfusion of insulin in the blood ?

Sorry my English not very good so I'm sorry
 
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HbA1c is just a test, a measure/count of glycated red blood cells.
 
Guzzler said:
HbA1c is just a test, a measure/count of glycated red blood cells.
Click to expand...
But why the higher the level of Hba1c was controlling the level of blood glucose is difficult
 
The A1c can tell you how well or how poorly you are managing your blood glucose levels, nothing more.
The better your management the lower your A1c score will be.

Insulin response can be measured but this is done using a totally different method of testing and even in Britain this test is not available free of charge.
 
I want to say that a1c is the glucose adhesion of red blood cells

And that the greater the adhesion of glucose to the blood cells, the control of diabetes was more difficult


Either abbreviation Hba1c I know it test gives you an idea of the level of glucose in the last few months
 
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Yes, the greater the glycation (glucose attached to haemoglobin cells) the higher the HbA1c test will be. However, red blood cells die off within about 120 days and are replaced by brand new cells which have no glucose attached to them initially, so if we work very hard to control the amount of glucose we eat, helped by medication if necessary, we have a good chance of reducing the glycation and future HbA1c tests should show less glycation as there will be less glucose in the blood stream.
 

It's the other way round.

If there is more glucose in you blood, ( due to poor control or otherwise ) , more will stick to the red blood cells..

HbA1c is a indication of what your glucose levels have been over the blood cell's life times.

A high HbA1c is an indication of problems with glucose levels not a cause of it.

( it isn't as if a diabetic's blood cells were extra sticky )
 
I am sorry for the many questions but
We know that Hba1c levels play an important role in blood glucose

Blood glucose levels also play an important role in Hba1c

Just an illogical question

What if the blood changed to a person with diabetes would get a positive result at levels of BG
And what if the opposite

I think he will get a good result at least during the first few weeks

No matter how the blood is replaced I just give an example
 
Basically what happens is that glucose sticks to our red blood cells. We can think of HbA1c as the percent of red blood cells that are found to have glucose stuck on them. So a normal health person should have only about 5% red blood cells with glucose. The higher the %, the more diabetic we are...

Since red blood cells are typically renewed every 90-120 days, that is the snapshot of our glucose level.

Those with anomaly in red blood cells reproduction will have skewed, unreliable, misleading HbA1c.

Hope this simplifed explanation helps.
 
hichamgsm said:
What if the blood changed to a person with diabetes would get a positive result at levels of BG
And what if the opposite
Click to expand...

Do you mean if we had a blood transfusion using blood from a healthy person? Then yes, an HbA1c test soon after can show a lower result because a lot of the haemoglobin would have less glucose stuck to it. Also, if we lost some blood somehow, or donated it, as it takes a week or so for the amount of haemoglobin to renew itself and return to normal levels we would have less glycated haemoglobin in our blood streams during that period. The HbA1c test does rely on us having a normal amount of haemoglobin.
 
hichamgsm said:
I am sorry for the many questions but
We know that Hba1c levels play an important role in blood glucose

Blood glucose levels also play an important role in Hba1c
Click to expand...
The HbA1C number is a result of blood glucose levels over a period of time, it only tells you what has happened.

So yes I suppose if you replaced all my blood with someone else's who didn't haven't diabetes I would think in the first few weeks my HbA1C would be lower than normal, but only because you'd wiped out the history - which would bring the average down, it wouldn't effect my blood glucose level once I got back to doing normal stuff like living - this is speculation on my part.

Edit: I obviously type way too slow
 
Yes, that's exactly what I want to say
 
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