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Type 1 Diabetes
Toxicity of insulin due to phenol and metacresol
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<blockquote data-quote="urbanracer" data-source="post: 1942623" data-attributes="member: 140811"><p>I had been experiencing increasingly severe pains around the shoulder areas for over a year. Having read somewhere that diabetics have a higher incidence of frozen shoulder I assumed the muscle pains were related. Then around January time this year I also started to experience systemic rashes and anaphylaxis although I was not aware of changes in levels of exposure to a substance. I was taking up to 4 antihistamines a day (under doctor's orders I might add) to keep the allergy suppressed.</p><p></p><p>Reading through the PIL that comes with Mix25 and subsequently Abasaglar, I noticed that 1 in 10,000 users are likely to experience rashes and myalgia. After a discussion with an Endo' I got my basal changed to Levimir around September time and now here we are in mid-December and I am (almost) pain free and the systemic rashes have almost stopped.</p><p></p><p>A dermatologist previously dismissed the insulin as a trigger because I couldn't specifically confirm that reactions were occurring at injection sites. Strangely, I am now getting a clear reaction at the injection site from Levimir but the systemic rashes are not so bad.</p><p></p><p>This all started after taking insulin for 3 years without any issues, so have I simply built up a level of sensitivity to the bad stuff that's in insulin? It looks as though the drugs which are keeping me alive are also my worst enemy.</p></blockquote><p></p>
[QUOTE="urbanracer, post: 1942623, member: 140811"] I had been experiencing increasingly severe pains around the shoulder areas for over a year. Having read somewhere that diabetics have a higher incidence of frozen shoulder I assumed the muscle pains were related. Then around January time this year I also started to experience systemic rashes and anaphylaxis although I was not aware of changes in levels of exposure to a substance. I was taking up to 4 antihistamines a day (under doctor's orders I might add) to keep the allergy suppressed. Reading through the PIL that comes with Mix25 and subsequently Abasaglar, I noticed that 1 in 10,000 users are likely to experience rashes and myalgia. After a discussion with an Endo' I got my basal changed to Levimir around September time and now here we are in mid-December and I am (almost) pain free and the systemic rashes have almost stopped. A dermatologist previously dismissed the insulin as a trigger because I couldn't specifically confirm that reactions were occurring at injection sites. Strangely, I am now getting a clear reaction at the injection site from Levimir but the systemic rashes are not so bad. This all started after taking insulin for 3 years without any issues, so have I simply built up a level of sensitivity to the bad stuff that's in insulin? It looks as though the drugs which are keeping me alive are also my worst enemy. [/QUOTE]
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Toxicity of insulin due to phenol and metacresol
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