Yes, I've been using Tresiba for around 3 years and find it has a much flatter profile than Lantus, which didn't last the full 24 hours for me.I've taken Lantus 25U/d since it was released in the US. Now that it went generic this year my insurance company wants me to switch to either Basaglar (generic for Lantus) or Tresiba (degludec), which is the same "strength" as Lantus. Any forum members have any experience with Tresiba? Thanks in advance.
I've taken Lantus 25U/d since it was released in the US. Now that it went generic this year my insurance company wants me to switch to either Basaglar (generic for Lantus) or Tresiba (degludec), which is the same "strength" as Lantus. Any forum members have any experience with Tresiba? Thanks in advance.
Thanks to both of you. I did do a search before starting a new thread. There aren't many references to Tresiba here I've found. It only comes in pens, not vials like Lantus. Basaglar is the same way. They say use the same number of units as you do Lantus, which makes sense. Funny with my insurance I think it costs the same as Basaglar which I would have thought would be less than Lantus, but Basaglar is actually 30% more than Lantus was. US drug prices are criminal. I used to get my Lantus from Canada way cheaper than here (I couldn't get insurance with diabetes of course), and the good President Obama made that illegal of course.Hi @TheBigNewt - I was using Tresiba before I went onto the pump - absolutely recommend this, I found once i'd adjusted and become stable on my background dose that it was very good, as @robert72 has said it's a much flatter profile, only 1 injection a day. Don't rush adjustments on this though you will probably start on a third less and then gradually over a few weeks adjust to find your right dose.
I get my Tresiba in cartridges if that's what you mean, although not sure about availability in the USThere aren't many references to Tresiba here I've found. It only comes in pens, not vials like Lantus. Basaglar is the same way.
Yeah I used cartridges for Humulog I think. No Tresiba is only in disposable pens over here. 3cc each. 100IU or 200IU/ml probably 1.5cc.I get my Tresiba in cartridges if that's what you mean, although not sure about availability in the US
Thanks for that summary sir. First post, and from a practicioner no less, I'm honored! I noticed that in the randomized trial vs Lantus there was a slightly better A1C drop with Lantus over Tresiba. Like I said I don't get any site pain, and it's worked well for many years so I see no reason to change. I switched from Humulog to Novolog a few years back didn't note any difference with that either. Like I said event the Basaglar price is higher than Lantus was, but I'm my own prescriber (cards not endo) so I'll beat them at that game. Wish it came in vial though, so much more compact to carry around. I tried Levemir and that was definitely BID dosing.The studies suggest, as others have said, that the Lantus does not quite last the full 24 hours and 5% of folk need to take Lantus BD. Agree that Lantus can sting, it is slightly acidic to keep it soluble in the cartridge. If my patients were having bother with Lantus, I would switch to tresiba degludec and generally it was an improvement; I think Marc Evans of cardiff published his similar real world experience of switching to degludec. Degludec has dropped price in UK, but it is still more expensive than other long acting analogues. There is a good deal of flexibility in timing of the degludec dosse, which is useful if absent minded, busy or crossing time zones. Basaglar and lantus have the same amino acid sequence but their folding might be a bit different - they are biosimilar, not biosame, so I would not trust them to be exactly the same. So, if you are happy with your present control, I would not switch - if your present control is good (however one defines this), then a switch cannot make it better, but might make it worse. If you are not happy with your present control, then a switch is reasonable, but a switch to degludec is probably going to be more of an improvement than a switch to the bio-similar insulin. Hope this is helpful Best wishes.
Thanks for that summary sir. First post, and from a practicioner no less, I'm honored! I noticed that in the randomized trial vs Lantus there was a slightly better A1C drop with Lantus over Tresiba. Like I said I don't get any site pain, and it's worked well for many years so I see no reason to change. I switched from Humulog to Novolog a few years back didn't note any difference with that either. Like I said event the Basaglar price is higher than Lantus was, but I'm my own prescriber (cards not endo) so I'll beat them at that game. Wish it came in vial though, so much more compact to carry around. I tried Levemir and that was definitely BID dosing.
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