I've been on trulicity for over a year now, and had some symptoms such as slight nausea and feeling uncomfortably over full, but not a lot of trumping going on!
I welcomed the over full feeling because it stopped me overeating for a good six months, then after that I felt the appetite reduction was less. The more noticeable nausea side effects only lasted on and off for a few weeks I think.
For me it has been life changing because up until then I'd been getting ready for bariatric surgery, having lost all hope of getting control. It allowed me to try changing my way of eating and that change resulted in significant weight loss. The weight loss has slowed now but I'm fighting on.
Very importantly, my health has improved dramatically, and I do credit trulicity as a significant factor.