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Type 1 Diabetes
type 1. genetics
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<blockquote data-quote="tim2000s" data-source="post: 1221785" data-attributes="member: 30007"><p>I had quite a long chat with one of the Exeter researchers about this topic. Whilst there is a very clear genetic link within families with Type 2, Type 1 has much less of one. From what I've read, genetically they can probably identify that within a lineage there is likely to be autoimmune disorder (and typically, if you look at families where there are T1s, you will find other autoimmune issues, as well as multiple autoimmune issues within a T1), but it's not obvious which of these will manifest or what might trigger it. Classic examples include Thyroid issues, Vitiligo, Psoriasis, some forms of arthritis, and of course T1 diabetes. </p><p></p><p>As a result, it's much harder to trace a specific genetic lineage within T1.</p></blockquote><p></p>
[QUOTE="tim2000s, post: 1221785, member: 30007"] I had quite a long chat with one of the Exeter researchers about this topic. Whilst there is a very clear genetic link within families with Type 2, Type 1 has much less of one. From what I've read, genetically they can probably identify that within a lineage there is likely to be autoimmune disorder (and typically, if you look at families where there are T1s, you will find other autoimmune issues, as well as multiple autoimmune issues within a T1), but it's not obvious which of these will manifest or what might trigger it. Classic examples include Thyroid issues, Vitiligo, Psoriasis, some forms of arthritis, and of course T1 diabetes. As a result, it's much harder to trace a specific genetic lineage within T1. [/QUOTE]
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