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Message: <blockquote data-quote="picklebean" data-source="post: 337191" data-attributes="member: 38236">I'm T1 and have been on metformin for over 10 years now.  I started on the twice-a-day regime like you and then moved to the slow-release once-a-day version.  Both times I started the new med I had an upset stomach for about a month and couldn't be too far from a toilet for fear of disasterous consequences! :lol: So I would think that the symptoms you mention are probably because of the meds, but keep an eye them and if they persist, see your doctor.At this point I can't actually remember why I went on the slow-release version or what benefits it gave me over the other type... it was so long ago!I also can't remember having any significant benefit or changes like weight-loss or reduction in blood sugars.  But, that said, I think it may be a case of I would be much 'worse' without the metformin.  Other people may be able to tell you whether or not they have seen signifcant weight loss or other such effects.  I have polycystic ovarian syndrome and insulin resistance and I think the metformin is supposed to help with this by making my body more sensitive to the insulin I take, but as I say, I never saw a dramatic change in my condition/needs.Good luck and I hope you find that it helps!</blockquote>

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