NicoleC1971
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https://www.jci.org/articles/view/60016/figure/5
Interesting twitter thread led me here (via Gabor Endosi who's worth a follow on matters metabolic) re the differences between insulin you inject versus insulin you make yourself.
Warning it involves mice but the interesting bit is the concept that exogenous insulin doesn't inhibit insulin's antagonist hormone - glucagon due to the way it hits the liver. So you get plenty to push energy into the cells but it s less effective at the muscular and liver level.
Interesting twitter thread led me here (via Gabor Endosi who's worth a follow on matters metabolic) re the differences between insulin you inject versus insulin you make yourself.
Warning it involves mice but the interesting bit is the concept that exogenous insulin doesn't inhibit insulin's antagonist hormone - glucagon due to the way it hits the liver. So you get plenty to push energy into the cells but it s less effective at the muscular and liver level.