antonov124
Newbie
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antonov124 said:other meds
simvastatin 80mg
anti-deperessants
ramapril (was on adalat but taken off as my kidneys were flushing ketones)
The risk of myopathy, including rhabdomyolysis, is greater in patients on simvastatin 80 mg compared with other statin therapies with similar or greater LDL-C-lowering efficacy and compared with lower doses of simvastatin. Therefore, the 80-mg dose of ZOCOR should be used only in patients who have been taking simvastatin 80 mg chronically (e.g., for 12 months or more) without evidence of muscle toxicity [see DOSAGE AND ADMINISTRATION, Restricted Dosing for 80 mg]. If, however, a patient who is currently tolerating the 80-mg dose of ZOCOR needs to be initiated on an interacting drug that is contraindicated or is associated with a dose cap for simvastatin, that patient should be switched to an alternative statin with less potential for the drug-drug interaction. Patients should be advised of the increased risk of myopathy, including rhabdomyolysis, and to report promptly any unexplained muscle pain, tenderness or weakness. If symptoms occur, treatment should be discontinued immediately.
(My bolding and underlining above)Drug Interactions
The risk of myopathy and rhabdomyolysis is increased by high levels of statin activity in plasma. Simvastatin is metabolized by the cytochrome P450 isoform 3A4. Certain drugs which inhibit this metabolic pathway can raise the plasma levels of simvastatin and may increase the risk of myopathy. These include itraconazole, ketoconazole, and posaconazole, the macrolide antibiotics erythromycin and clarithromycin, and the ketolide antibiotic telithromycin, HIV protease inhibitors, boceprevir, telaprevir, the antidepressant nefazodone, or large quantities of grapefruit juice ( > 1 quart daily). Combination of these drugs with simvastatin is contraindicated.
antonov124 said:...Am not sure what i should really be doing as I feel i'm being paid lip service and its all my own fault
No eye or foot screening?antonov124 said:Should i only be seen by my practice nurse for my diabetes, or should i be seen elsewhere in the NHS.
If it was 8.6 that would be "worrying", 18.6 would be better described as "highly alarming". (Even as a maximum.)Have seen other posts re testing strips and i have no trouble obtaining them . my bloods average 18.6 and the nurse doesn't seem phased by this but i find it worrying.
Actually the non "sugary" ones may well be the worst. Because of a quirk of the chemistry involved disaccharides equate to 106% sugar and polysaccharides equate to 111% sugar.Daibell said:Hi. Yes, losing weight is obviously the priority but note that any carb is 'naughty', not just sugary ones,
If you are going to eat a high carbohydrate diet, from the point of view of blood glucose control, sucrose or lactose @53% glucose are a much better option than amylose or amylopectin @111% glucose. Most possible high carbohydrate diets would also be high in glucose diets. Even those which didn't have a specific class (of 1/3) for foods high in glucose polysaccharides.if you take too many or the portion size is too large. Keeping fat down will help reduce calories, but note that reducing the carbs is more important than the fats as reducing carbs will help get the sugars down as well; reducing fats won't.
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