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Type 2: Low carb cannot repair damaged beta cells
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<blockquote data-quote="ziggy_w" data-source="post: 2365973" data-attributes="member: 323454"><p>[USER=422465]@Tannith[/USER],</p><p></p><p>You might be interesting in the following scientific article <a href="https://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00114-4" target="_blank">https://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00114-4</a>. It says that glucotoxicity (toxicity due to high blood sugars) causes beta cells to differentiate into other types of cells (they turn into delta cells if I remember correctly) and once blood sugars normalize due to insulin treatment, they redifferentiate into beta cells.</p><p></p><p>So, if normalizing blood sugar levels due to insulin leads to a recovery of at least some beta cells, why wouldn't normalizing blood sugar levels due to low carbing do the same thing (even without weight loss)?</p><p></p><p>I agree with you that a fatty pancreas is a problem for many, if not most, T2s. However, I also believe that pancreas fat can also be be reduced by cutting out fructose (and possibly other carbs) rather than just reducing calories. </p><p></p><p>Dr. Robert Lustig has conducted a study (<a href="https://www.ucsf.edu/news/2017/08/408151/switching-sugar-starch-leads-less-fatty-liver-kids" target="_blank">https://www.ucsf.edu/news/2017/08/408151/switching-sugar-starch-leads-less-fatty-liver-kids</a>) where he substituted fructose (as in table sugar) with starchy carbs in children while keeping calories the same. What he observed was that while they did not lose weight, they lost fat from the liver. The question that follows from this is why wouldn't we also lose weight from other internal organs such as the pancreas, when we are losing fat from the liver?</p></blockquote><p></p>
[QUOTE="ziggy_w, post: 2365973, member: 323454"] [USER=422465]@Tannith[/USER], You might be interesting in the following scientific article [URL]https://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00114-4[/URL]. It says that glucotoxicity (toxicity due to high blood sugars) causes beta cells to differentiate into other types of cells (they turn into delta cells if I remember correctly) and once blood sugars normalize due to insulin treatment, they redifferentiate into beta cells. So, if normalizing blood sugar levels due to insulin leads to a recovery of at least some beta cells, why wouldn't normalizing blood sugar levels due to low carbing do the same thing (even without weight loss)? I agree with you that a fatty pancreas is a problem for many, if not most, T2s. However, I also believe that pancreas fat can also be be reduced by cutting out fructose (and possibly other carbs) rather than just reducing calories. Dr. Robert Lustig has conducted a study ([URL]https://www.ucsf.edu/news/2017/08/408151/switching-sugar-starch-leads-less-fatty-liver-kids[/URL]) where he substituted fructose (as in table sugar) with starchy carbs in children while keeping calories the same. What he observed was that while they did not lose weight, they lost fat from the liver. The question that follows from this is why wouldn't we also lose weight from other internal organs such as the pancreas, when we are losing fat from the liver? [/QUOTE]
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