Type 3 diabetes I think

Hi there,

There is a type 3, also known as monogenic diabetes or MODY. I was diagnosed as a type 1 in 1984 but last year my consultant made a connection between the medical conditions I have and I had a c-peptide test followed by genetic testing which confirmed a monogenic rather than autoimmune cause. Because it is a genetic condition they look for a family history of diabetes, although in my case there was no family history.

Have a look at http://www.diabetesgenes.org/ as this is a good starting point for info and Exeter carry out the c-peptide and genetic testing.

My DSN, who is also a regional genetic diabetes nurse will be altering my treatment from insulin to Gliclazide, but whether this will work after almost 30 years of injections is anybody's guess!

_petal_


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The type 3 diabetes defined elsewhere on diabetes.co.uk here seems to be a bit different to the monogenic diabetes described above.

http://www.diabetes.co.uk/type3-diabetes.html

which starts-

Type 3 diabetes is a title that has been proposed for Alzheimer's disease which results from resistance to insulin in the brain.

• Also see: Diabetes symptoms

Studies carried out by the US Brown Medical School research team identified the possibility of a new form of diabetes after finding that insulin is produced by the brain as well as the pancreas.

I see where the confusion is, as lots of journal articles refer to 'Maturity-Onset Diabetes of the Young Type 3', as in the following article:

http://m.care.diabetesjournals.org/content/31/2/306.full

This is very different to the Alzheimer's Type 3 also described. There is lots to be careful of when classifying the different types!


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I think officially there is only 1, 1.5 and 2............

my opinion is that there is only 1 and 2, with different variants of 1.......