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Unpublished Data Review: The Minnesota Coronary Experiment (1968-73)
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<blockquote data-quote="Biggles2" data-source="post: 1657593" data-attributes="member: 406880"><p>This journal article below, published in <em><strong>BMJ</strong></em> in 2016, is well worth a read. The authors had previously recovered and reviewed unpublished data from the <em><strong>Sydney Diet Heart Study</strong></em>. In this paper, they review recovered unpublished data from the <strong><em>Minnesota Coronary Experiment</em></strong>. A snippet from their article is included below:</p><p><strong><em>Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)</em></strong></p><p style="margin-left: 20px"><strong> “Conclusions </strong>Available evidence from randomized controlled trials shows that replacement of saturated fat in the diet with linoleic acid effectively lowers serum cholesterol but does not support the hypothesis that this translates to a lower risk of death from coronary heart disease or all causes. Findings from the Minnesota Coronary Experiment add to growing evidence that incomplete publication has contributed to overestimation of the benefits of replacing saturated fat with vegetable oils rich in linoleic acid.”</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836695/?report=printable" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836695/?report=printable</a></p><p></p><p>And a link to newspaper review of the above BMJ article in the <strong><em>Washington Post</em></strong>:</p><p><a href="https://www.washingtonpost.com/news/wonk/wp/2016/04/12/this-study-40-years-ago-could-have-reshaped-the-american-diet-but-it-was-never-fully-published/?utm_term=.af0e53e71957" target="_blank">https://www.washingtonpost.com/news/wonk/wp/2016/04/12/this-study-40-years-ago-could-have-reshaped-the-american-diet-but-it-was-never-fully-published/?utm_term=.af0e53e71957</a></p></blockquote><p></p>
[QUOTE="Biggles2, post: 1657593, member: 406880"] This journal article below, published in [I][B]BMJ[/B][/I] in 2016, is well worth a read. The authors had previously recovered and reviewed unpublished data from the [I][B]Sydney Diet Heart Study[/B][/I]. In this paper, they review recovered unpublished data from the [B][I]Minnesota Coronary Experiment[/I][/B]. A snippet from their article is included below: [B][I]Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)[/I][/B] [INDENT][B] “Conclusions [/B]Available evidence from randomized controlled trials shows that replacement of saturated fat in the diet with linoleic acid effectively lowers serum cholesterol but does not support the hypothesis that this translates to a lower risk of death from coronary heart disease or all causes. Findings from the Minnesota Coronary Experiment add to growing evidence that incomplete publication has contributed to overestimation of the benefits of replacing saturated fat with vegetable oils rich in linoleic acid.”[/INDENT] [URL]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836695/?report=printable[/URL] And a link to newspaper review of the above BMJ article in the [B][I]Washington Post[/I][/B]: [URL]https://www.washingtonpost.com/news/wonk/wp/2016/04/12/this-study-40-years-ago-could-have-reshaped-the-american-diet-but-it-was-never-fully-published/?utm_term=.af0e53e71957[/URL] [/QUOTE]
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