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Diabetes Management
Diabetes Medication and Drugs
Metformin/Biguanides
Very long term use of Metformin plus reasons for use
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<blockquote data-quote="LittleGreyCat" data-source="post: 2663603" data-attributes="member: 6467"><p>Metformin is the first drug of choice for newly diagnosed T2s.</p><p>My understanding is that Metformin reduces insulin resistance and can also reduce appetite.</p><p>The reasoning is that the vast majority of newly diagnosed T2s are suffering from insulin resistance and associated hunger issues.</p><p></p><p>My main question is, is Metformin still effective for people who have little or no insulin resistance but a reduced production of insulin.</p><p></p><p>I am heading for a medication review within the next 3 months, prompted by higher HbA1c (7.9%) and lower eGFR (40).</p><p></p><p>eGFR of 45 is the point at which you should consider reducing or stopping Metformin.</p><p></p><p>I am having another test to check if my eGFR really has gone that low as it is well below trend.</p><p></p><p>I am therefore thinking of the implications of stopping Metformin and wondering how much good it is doing me these days.</p><p>Diagnosed nearly 16 years now.</p><p></p><p>Also wondering if I should push for a cPeptide test to see how much insulin I am still producing, as this could be a factor in prescribing SGLT2 inhibitors.</p></blockquote><p></p>
[QUOTE="LittleGreyCat, post: 2663603, member: 6467"] Metformin is the first drug of choice for newly diagnosed T2s. My understanding is that Metformin reduces insulin resistance and can also reduce appetite. The reasoning is that the vast majority of newly diagnosed T2s are suffering from insulin resistance and associated hunger issues. My main question is, is Metformin still effective for people who have little or no insulin resistance but a reduced production of insulin. I am heading for a medication review within the next 3 months, prompted by higher HbA1c (7.9%) and lower eGFR (40). eGFR of 45 is the point at which you should consider reducing or stopping Metformin. I am having another test to check if my eGFR really has gone that low as it is well below trend. I am therefore thinking of the implications of stopping Metformin and wondering how much good it is doing me these days. Diagnosed nearly 16 years now. Also wondering if I should push for a cPeptide test to see how much insulin I am still producing, as this could be a factor in prescribing SGLT2 inhibitors. [/QUOTE]
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Very long term use of Metformin plus reasons for use
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