There's been a few situations where I got so damned engrossed in a game that I just didn't notice that I was slipping into a hypo.
Still, the pressure of war, when there's five snipers trying ta take ya out, man's gotta find his carbs where he can! Maybe get on to Rockstar and start getting them to hide real easter eggs around the place.
There's so many reasons for hypos, and they can be so unpredictable, I don't think it's really anything to do with gaming as such, other than maybe just, as above, getting so tied up in it, easy to miss the onset.