Reply to Thread

Guest, we'd love to know what you think about the forum! Take the Diabetes Forum Survey 2025 »

Message: <blockquote data-quote="SimonCrox" data-source="post: 1957928" data-attributes="member: 388174">The catch is "protein binding". All these drugs are bound to protein in the blood, so that if on gliclazide, adding another protein bound drug like aspirin should theoretically displace the gliclazide from the protein so more free gliclazide around so more effect eg hypos.I have never seen this happen despite seeing a lot of people on gliclazide and aspirin. Also, if one is on a regular dose of aspirin / NSAID, then gently adding in gliclazide on top is not going to lead to a sudden surge in free active gliclazide in blood stream.So, no worries there.As above, I would be more bothered by the use of ibuprofen - if it cannot be avoided, then that is the case; ibuprofen and NSAIDs are very effective painkillers for many people in an easy to take dose, but there are side effects, so good to see if a topical NSAID would work or smaller dose; ibuprofen or naproxen seem to be the safestbest wishes</blockquote>

Top Bottom