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<blockquote data-quote="ianf0ster" data-source="post: 2147300" data-attributes="member: 506169"><p>Hi,</p><p> I have now watched the video. As is usual with these sort of things it goes all over the place to find anything which may possibly improve lifespan - genetics; supplement for mice, so presumably not a drug but they give no details of what it is; 'simulated Fasting' (whatever that entails) for 5 days every 3 months; Metformin.</p><p></p><p>With the possible exception of genetics (having the right parents) I'm not convinced that they there is enough evidence to support any of these yet in humans at least.</p><p>I feel it is important to understand that with the Metformin, the idea is that if it can be shown to 'protect against CVD, Dementia, Cancer and Diabetes then it may increase average (though not individual) lifespan. </p><p></p><p>You may find this confusing but consider this: The 4 diseases mentioned are the biggest killers of middle aged to slightly elderly people, but the thing that most really elderly people die from is a simple infection such as pneumonia - their body and immune system gets so weak that they can no longer recover from simple but serious infections. </p><p></p><p>There is a study which shows for example that in the over 65's the group with the LDL in the highest quarter of the study population lived a statistically significant while longer than those in the lowest LDL quarter of the study. Naturally the Statin manufacturers are keen to obscure this by saying that that group with higher LDL are probably on statins.</p><p>So if you believe the Pharmas, not only are this quartile of the study population on statins (statin use or none was not recorded in that study) <strong>but also the statins were not reducing their LDL </strong>(like they are prescribed to do)<strong> and the statins were 'protecting them from the diseases of old age.</strong> <span style="color: #0059b3"><em>-That is far too big a leap of faith (on no evidence) for me!</em></span></p><p><strong></strong></p><p><strong></strong></p></blockquote><p></p>
[QUOTE="ianf0ster, post: 2147300, member: 506169"] Hi, I have now watched the video. As is usual with these sort of things it goes all over the place to find anything which may possibly improve lifespan - genetics; supplement for mice, so presumably not a drug but they give no details of what it is; 'simulated Fasting' (whatever that entails) for 5 days every 3 months; Metformin. With the possible exception of genetics (having the right parents) I'm not convinced that they there is enough evidence to support any of these yet in humans at least. I feel it is important to understand that with the Metformin, the idea is that if it can be shown to 'protect against CVD, Dementia, Cancer and Diabetes then it may increase average (though not individual) lifespan. You may find this confusing but consider this: The 4 diseases mentioned are the biggest killers of middle aged to slightly elderly people, but the thing that most really elderly people die from is a simple infection such as pneumonia - their body and immune system gets so weak that they can no longer recover from simple but serious infections. There is a study which shows for example that in the over 65's the group with the LDL in the highest quarter of the study population lived a statistically significant while longer than those in the lowest LDL quarter of the study. Naturally the Statin manufacturers are keen to obscure this by saying that that group with higher LDL are probably on statins. So if you believe the Pharmas, not only are this quartile of the study population on statins (statin use or none was not recorded in that study) [B]but also the statins were not reducing their LDL [/B](like they are prescribed to do)[B] and the statins were 'protecting them from the diseases of old age.[/B] [COLOR=#0059b3][I]-That is far too big a leap of faith (on no evidence) for me![/I][/COLOR] [B] [/B] [/QUOTE]
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