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What would cause persistently elevated Glucose levels but a perfectly normal HbA1c???
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<blockquote data-quote="phoenix" data-source="post: 592972" data-attributes="member: 12578"><p>What do you mean by fasting?</p><p>Is it a home test done immediately upon waking, Is it when you have got out of bed and done a few things ?</p><p>Are they lab tests when you have been awake for two hours before the test takes place?</p><p>'Fasting levels' vary between time of day and also things like stress effects them. So might a long walk to the test lab.</p><p> </p><p> To see if you have persistent high glucose you would need to look at other times of day</p><p> </p><p>Although the HbA1c is a good measure over time, the bonding process ie the joining of glucose to the red blood cell is a relatively slow reaction and so if you are only at that level for a brief time it won't occur. (which is why non diabetics can regularly have brief periods with higher glucose but still have quite normal HbA1cs)</p><p> </p><p>There are though some conditions that can result in shorter than normal red cell life so artificially lower HbA1c .</p><p>If you have had some blood loss or have donated blood recently, that could lower HbA1c</p><p>. If you have an African, Mediterranean or SE Asian heritage then this could be relevant : <a href="http://diabetes.niddk.nih.gov/dm/pubs/traitA1C/index.aspx" target="_blank">http://diabetes.niddk.nih.gov/dm/pubs/traitA1C/index.aspx</a></p><p>also this interview mentions other reasi</p><p><a href="http://asweetlife.org/feature/interview-dr-zachary-bloomgarden-on-the-hba1c-assay/" target="_blank">http://asweetlife.org/feature/interview-dr-zachary-bloomgarden-on-the-hba1c-assay/</a></p></blockquote><p></p>
[QUOTE="phoenix, post: 592972, member: 12578"] What do you mean by fasting? Is it a home test done immediately upon waking, Is it when you have got out of bed and done a few things ? Are they lab tests when you have been awake for two hours before the test takes place? 'Fasting levels' vary between time of day and also things like stress effects them. So might a long walk to the test lab. To see if you have persistent high glucose you would need to look at other times of day Although the HbA1c is a good measure over time, the bonding process ie the joining of glucose to the red blood cell is a relatively slow reaction and so if you are only at that level for a brief time it won't occur. (which is why non diabetics can regularly have brief periods with higher glucose but still have quite normal HbA1cs) There are though some conditions that can result in shorter than normal red cell life so artificially lower HbA1c . If you have had some blood loss or have donated blood recently, that could lower HbA1c . If you have an African, Mediterranean or SE Asian heritage then this could be relevant : [url]http://diabetes.niddk.nih.gov/dm/pubs/traitA1C/index.aspx[/url] also this interview mentions other reasi [url]http://asweetlife.org/feature/interview-dr-zachary-bloomgarden-on-the-hba1c-assay/[/url] [/QUOTE]
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What would cause persistently elevated Glucose levels but a perfectly normal HbA1c???
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