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When people say there is a cure for diabetes.
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<blockquote data-quote="phoenix" data-source="post: 917119" data-attributes="member: 12578"><p>Edit:this isn't really on topic, I was following the thread.</p><p>I've actually never heard anyone except the occasional scam merchants on here say that there is a cure for diabetes.</p><p>I think that we may be able to prevent some types in the future (possibly very near future)</p><p></p><p>Mitochondrial diabetes for example could be eliminated (except for new mutations) through the use of donor mitochondrial DNA (3 person babies), controversial but approved in the UK. Regulations on it's use are being formulated .at the moment</p><p><a href="http://www.bbc.com/news/health-31594856" target="_blank">http://www.bbc.com/news/health-31594856</a></p><p>We also have the theoretical capability of making heritable changes in DNA by 'editing' using the Crispr technique so it is possible that other sorts of MODY which involve the mutation in one gene could be prevented.</p><p> <a href="http://news.berkeley.edu/2015/03/19/scientists-urge-caution-in-using-new-crispr-technology-to-treat-human-genetic-disease" target="_blank">http://news.berkeley.edu/2015/03/19/scientists-urge-caution-in-using-new-crispr-technology-to-treat-human-genetic-disease</a></p><p></p><p></p><p>Type 1 is harder, it's heritable but it's much more complicated since genes only predispose , something else triggers it in some and not in others ( and there are far more genes involved so lots of combinations possible from two parents ) </p><p>They are still working on techniques to prevent or intervene in the 'pre diabetic' period.. Even if they succeed It won't help those who don't know they have a genetic susceptibility ie the majority.</p><p></p><p>Cure is a different matter for T1 my big hope for the future is with encapsulated stem cells <a href="https://www.jdrf.org.uk/news/latest-news/breaking-news-encapsulated-stem-cells-implanted-in-to-person-with-type-1-diabetes-for-first-time" target="_blank">https://www.jdrf.org.uk/news/latest-news/breaking-news-encapsulated-stem-cells-implanted-in-to-person-with-type-1-diabetes-for-first-time</a></p><p></p><p>Type 2 is hard because it's far more than one condition.Professor Gale suggested that it was category error : a disease in search of a definition , a 'ragbag' of conditions. He suggests it should be called idiopathic (don't know cause) hyperglycemia</p><p><a href="http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62207-7/abstract" target="_blank">http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62207-7/abstract</a> (there's a video in which he discusses what this means in context of both treatment and cure)</p></blockquote><p></p>
[QUOTE="phoenix, post: 917119, member: 12578"] Edit:this isn't really on topic, I was following the thread. I've actually never heard anyone except the occasional scam merchants on here say that there is a cure for diabetes. I think that we may be able to prevent some types in the future (possibly very near future) Mitochondrial diabetes for example could be eliminated (except for new mutations) through the use of donor mitochondrial DNA (3 person babies), controversial but approved in the UK. Regulations on it's use are being formulated .at the moment [URL]http://www.bbc.com/news/health-31594856[/URL] We also have the theoretical capability of making heritable changes in DNA by 'editing' using the Crispr technique so it is possible that other sorts of MODY which involve the mutation in one gene could be prevented. [URL]http://news.berkeley.edu/2015/03/19/scientists-urge-caution-in-using-new-crispr-technology-to-treat-human-genetic-disease[/URL] Type 1 is harder, it's heritable but it's much more complicated since genes only predispose , something else triggers it in some and not in others ( and there are far more genes involved so lots of combinations possible from two parents ) They are still working on techniques to prevent or intervene in the 'pre diabetic' period.. Even if they succeed It won't help those who don't know they have a genetic susceptibility ie the majority. Cure is a different matter for T1 my big hope for the future is with encapsulated stem cells [URL]https://www.jdrf.org.uk/news/latest-news/breaking-news-encapsulated-stem-cells-implanted-in-to-person-with-type-1-diabetes-for-first-time[/URL] Type 2 is hard because it's far more than one condition.Professor Gale suggested that it was category error : a disease in search of a definition , a 'ragbag' of conditions. He suggests it should be called idiopathic (don't know cause) hyperglycemia [URL]http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62207-7/abstract[/URL] (there's a video in which he discusses what this means in context of both treatment and cure) [/QUOTE]
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