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<blockquote data-quote="phoenix" data-source="post: 865581" data-attributes="member: 12578"><p>Lada = latent autoimmune diabetes in adults.</p><p>MODY stands for maturity onset diabetes of the young This was named before they really knew what it was and before they realised that there were several versions. A better name is perhaps monogenic diabetes which reflects that it is caused by a genetic mutation. (different types have different mutations) . It is an inherited condition but as you say you could be the first, or perhaps your version doesn't show up until later and your parent was never diagnosed.(??).</p><p></p><p>I do think that a lot of weight loss seems to be more associated with T1 (LADA) than T2. MODY not so sure. I don't get the impression that many T2s are diagnosed with unintentional weight loss Your doctor is at least investigating which is good (my doc did the same but I got the LADA diagnosis)</p><p></p><p>For several types of MODY treatment with sulfs is very much better than with metformin and often only use very low doses. It's because it works by bypassing the normal signalling system to the beta cells telling them to make and release insulin. As I understand it, It is the signalling system that is deficient in some MODYs</p><p>Heres a graph showing how much better it is with MODY 3 (source Univ. Copenhagen Global Diabetes course)</p><p>[ATTACH]13574[/ATTACH]</p></blockquote><p></p>
[QUOTE="phoenix, post: 865581, member: 12578"] Lada = latent autoimmune diabetes in adults. MODY stands for maturity onset diabetes of the young This was named before they really knew what it was and before they realised that there were several versions. A better name is perhaps monogenic diabetes which reflects that it is caused by a genetic mutation. (different types have different mutations) . It is an inherited condition but as you say you could be the first, or perhaps your version doesn't show up until later and your parent was never diagnosed.(??). I do think that a lot of weight loss seems to be more associated with T1 (LADA) than T2. MODY not so sure. I don't get the impression that many T2s are diagnosed with unintentional weight loss Your doctor is at least investigating which is good (my doc did the same but I got the LADA diagnosis) For several types of MODY treatment with sulfs is very much better than with metformin and often only use very low doses. It's because it works by bypassing the normal signalling system to the beta cells telling them to make and release insulin. As I understand it, It is the signalling system that is deficient in some MODYs Heres a graph showing how much better it is with MODY 3 (source Univ. Copenhagen Global Diabetes course) [ATTACH]13574[/ATTACH] [/QUOTE]
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