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You can measure your own Insulin Resistance !
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<blockquote data-quote="Oldvatr" data-source="post: 1567275" data-attributes="member: 196898"><p>I agree with the points you make here, but I am still having difficulty understanding the theory behind the formula, and how it mught relate to either my level of resistance to insulin, or even my level of insulin in my bloodstream.</p><p></p><p>If we forget the log function and the times 2 factor which are fixed values, the two variables are fasting trigs and fasting bgl.</p><p>Now my trigs currently changes once a year which is the only time my GP will authorise a lipid panel blood check, What it does on the remaining 364.25 days I have not a jot of evidence,</p><p></p><p>My FBGL varies on a daily basis, and can be heavily influenced by what I ate the night before, So unless there is a mechanism for averaging it before putting it into the formula than it is also just a moment in time, but not indicative of where I am at generally. (Note the lab check is also not daily and tends to be a 3 monthly or yearly blood test like the trigs check mentioed above)</p><p></p><p>So I have this dilemma, The formula is very dependant on what my last meal was before the sample was taken, and may jump suddenly once a year. How does it explain how successfully my insulin is generated or utilised? If I change my meds regime during the year, or change my diet during the year then these may have strong influence on the figures. </p><p></p><p>This is why I prefer to consider the OGTT as a basis for measuring my actual resistance by tracking the first response insulin phase following a defined step change stimulus. I think that with the introduction of CGMs then they will be able to develop a support app to measure the AUC (area under curve) of the response as an automatic function, so making the measurement repeatable and open to all without needing a lab check in the back room.</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 1567275, member: 196898"] I agree with the points you make here, but I am still having difficulty understanding the theory behind the formula, and how it mught relate to either my level of resistance to insulin, or even my level of insulin in my bloodstream. If we forget the log function and the times 2 factor which are fixed values, the two variables are fasting trigs and fasting bgl. Now my trigs currently changes once a year which is the only time my GP will authorise a lipid panel blood check, What it does on the remaining 364.25 days I have not a jot of evidence, My FBGL varies on a daily basis, and can be heavily influenced by what I ate the night before, So unless there is a mechanism for averaging it before putting it into the formula than it is also just a moment in time, but not indicative of where I am at generally. (Note the lab check is also not daily and tends to be a 3 monthly or yearly blood test like the trigs check mentioed above) So I have this dilemma, The formula is very dependant on what my last meal was before the sample was taken, and may jump suddenly once a year. How does it explain how successfully my insulin is generated or utilised? If I change my meds regime during the year, or change my diet during the year then these may have strong influence on the figures. This is why I prefer to consider the OGTT as a basis for measuring my actual resistance by tracking the first response insulin phase following a defined step change stimulus. I think that with the introduction of CGMs then they will be able to develop a support app to measure the AUC (area under curve) of the response as an automatic function, so making the measurement repeatable and open to all without needing a lab check in the back room. [/QUOTE]
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