I have been having real problems with having to run to the toilet all the time and could not go far from a toilet. The other day I was out for a meal with friends and had to keep getting up to go to the loo, by the end of the day I was knackered ! I thought I have to get a break from this - granted it is not TOO bad every day but is still there. I did not take any of my diabetes medication yesterday or today because I felt my stomach needed a rest.!! It has been great not having to run - and I mean run - to the loo and my stomach has felt a lot better. I have tried the SR tablets and they made no difference. I know this is not a good thing to do and I will start taking it in a couple of days again but does anyone know if I will have done a lot of damage to my health by doing this, my readings have not been any different from what they are when taking the medication. The reason I ask this as well is because I am going away for the weekend soon and will be on a long bus journey and I thought I might be able to do this again so I do not have any accidents !! I would be glad of any advice anyone can give me, I am so sick of taking all this medication, I have continued to take my high blood pressure ones but stopped the Statins a few weeks ago and have found such a difference in leg pain and sleep pattern. :?