I've been Type 2 for over 20 years and was put on Metformin immediately. I suffered through the years of taking Metformin but thought I just had to get on with it as I was told it was mega important for treatment of my diabetes. Symptoms worsened with terrible gut problems and, as another member mentioned, I was having to organise my life around proximity to the loo. Even then I wasn't very confident and wouldn't go out anywhere unless I had to because I also felt rubbish all the time. Eventually a couple of years ago I made the decision that I'd rather risk dying early of some complication than continuing to live feeling so ill so without consulting doctor (who never seemed that interested in my problems with Metformin) I stopped taking it. I noticed absolutely no difference in my blood glucose, but if I had I would have compensated by taking an increased dose of insulin anyway. However, what a difference to my life!!! After all those years of misery on Sukkarto, Glucophage, normal and extended release, moving to taking none of them brought me back to living a life instead of enduring it. So I'd say, if you're prescribed any of these things, take them for long enough to see if your body can cope. If not - ask for the extended release - ask for another manufacturer of Metformin - try them all if necessary BUT - if you really feel that bad, as I did, talk to your GP about NOT taking them. I can't tell you how much I regret having taken them for so long when they clearly didn't agree with me! Fortunately for me, having done the low carb high fat diet for quite a while, I've now lost loads of weight, feel terrific and, best of all, have stopped taking insulin too. Good luck with metformin.