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Thanks, brilliant. The issue is that i am doing all possible what i can do anyway to manage T2 with low-carb and proper diet, i understand there is no way to reverse CAC and if i know i have a score, there is nothing that will help me just being getting freaked out? There is not much i can...

I understand that having delayed diagnosis and being diabetic and prediabetic for long will eventually increase your glycation, oxidation stress and atherosclerosis eventually. The more reliable way to know how clean your arteries are the CAC score. I believe i have been diabetic several years...

So what you are saying is that its better to have a more sustained spike of less than 7 because it will release less insulin and will avoid the damages of hyperinsulenmia ?

Both CGM and finger testing and they tally mostly.

So this is again a dilemma that i am not able to figure out despite all the literature and experiments i have done so far in the last 2 years. So here is the case. When i eat a heavy protein/fat meal, my glucose stays elevated for 3-4 hours (in the range of 6.5-7 mmol). Now if i eat less protein...

Hi thanks for showing your interest. In 2020 when i was diagnosed with a1c of 78 my eye exam was all clear. After a year when i went to a1c in non-diabetic range, my eye exam showed some background retinopathy (this March), that is where i started reading again and found how G6PD can increase...

No i have not tested but this study reveals and I could correlate all metabolic classic symptoms and my BGs were non-diabetic https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-021-00911-6#:~:text=Regarding%20the%20oxidative%20stress%20status,levels%20(p%3C0.001).

Yes its a blessing in disguise for women but a killer for men !

Oh sorry, I didn't think that way. I added two studies in my reply, but there are more and because they are only few, they might be just repetition. So anyone who has interest in this topic, which i am sure many will have because i don't see this discussed anywhere on the forum and i was...

I know its a catch 22 situation, neither do i want to go that route, its just that when loosened things a bit last few months, i got diabetic symptoms even though as you said i was in healthy a1c range. Regarding oxidative stress, people with G6PD and diabetes have 6 times more oxidative stress...

Thanks, yes that is what i am exploring and weighing metformin in a hope of adding some more fun to life :)

You need to Google it, there are plenty of reference, studies and some articles, but here is couple i know https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8740051/ https://diabetesjournals.org/care/article/44/4/1059/138596/Rapid-Changes-in-Serum-Testosterone-in-Men-With

I have come across few studies that show metformin can reduce testosterone levels significantly and leads to low sex-drive and ED. I am just wondering anyone taking metformin has observed this affect or tested their testosterone levels before and after metformin therapy? You can Google it and...

Great, thanks. its encouraging. So I believe you have been taking this since 2017, so did you see metformin affect diminishing or it stayed the same all along?

I believe to the bone what you are saying but its not achieving a perfect a1c, its due to my G6PD deficiency that puts me 6 fold more oxidative stress if my BGs are running higher than 5.5 mmol. After my first year of remission, i started experimenting and let it lose a bit to enjoy life as you...

Great thanks. Can you share how your PP BGs look like normally and how fast they are back to fasting levels? Just need to understand how Metformin is affecting your fasting levels (2-3 hours after meals).

Hi there. In the absence of central obesity and insulin resistance as a type-2 diabetic, do you see your fasting sugar levels go to 80's (4's mmol) using metformin or any other medication for that matter? I am doing pretty low-carb but my baseline fasting sugars are close to 6 mmol. I have no...

Im talking of fasting insulin at 3, don't remember HOMA-IR but it was optimal.

Thanks. Insulin resistance is the main cause of T2 or where it starts from, but that is not the only cause. It could be beta cell damage, less insulin production and insulin production signaling (DPP & incretin signaling). I did HOMA-IR and im optimal range with fasting insulin at 3.

Hi all, Im just wondering what works for you if you decide to eat a carb heavy meal without an exaggerated glucose spike? I am mostly interested to understand if a one-time Metformin will help? or a one-time Acarbose dose? Without building these medications level in the blood (one-off?). There...