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@Leejparks give the PPI a go. I stopped it for 6 months cause I didn’t think it was helping and I lost weight. When I restarted it took a while to work. It can take up to 8 weeks to lower the ph in the small bowel for the Creon to work so might be worth persisting for a few weeks to see if it...

@Leejparks do you take a PPI? I noticed that without the PPI my sugars weren’t going up as the Creon is deactivated in acidic conditions. Your pancreas may not be producing any bicarbonate to buffer the acid for the Creon to work. Another issue could be bacterial overgrowth that causes...

I'm in the same boat. Unfortunately, taking a lot of creon but can't gain weight. I've tried everything. PPIs, antibiotics etc. but can't gain any weight. Its been over a year now. Initially I gained weight but then it stopped and stools worsened. Then I was put on rifaximin for 3 weeks and it...

Also would appreciate if anyone can share what their snacks look like - is it a biscuit, fruit etc in small quantities or something more substantial? I get the feeling my snacks are more like mini meals which is why I need to take a lot more Creon. I’m trying to gain weight so I need to eat a...

Thanks so much for replying. Yes I had malabsorption for a few months and rapidly lost 5 kg. It was mostly loose stool. I’ve gained back most of that weight although since the past month something changed and the Creon at the lower dose stopped working. I had to up Creon significantly (almost...

Hi all, I’m new to this forum. I’m type 1 recently diagnosed with pancreatic insufficiency. Please can you share any experiences you’ve had with Creon. I have calcification of the pancreas and just started taking Creon. I weigh 45kg but I’m taking a lot of Creon 3x25000 with main meals and...

Hi everyone, I’m hoping you can help me. I’ve been an insulin dependent diabetic for 20 years caused by calicification of the pancreas. About 4 months ago I was confirmed as having severe pancreatic insufficiency. Fecal elastase 8. I’ve been on Creon which seemed to work well for 3 months. I...