advice on mitochondria diabetes and treatment

[wardy123]

Does anyone know anything about the rare mitochondria diabetes as im in the middle of full diagnosis and find internet explanations too technical to understand?

 

[Dark Horse]

About 1% of people with diabetes have Maternally-Inherited Diabetes and Deafness (MIDD) rather than Type 1 or Type 2. MIDD is caused by a mutation in the DNA of the mitochondria - the parts of the cell involved in producing energy. We all inherit our mitochondria from our mothers, not our fathers so MIDD, like other mitochondrial diseases is inherited through the female line. The diabetes can resemble Type 1 or Type 2 and the deafness varies a lot between individuals - it tends to affect high-pitched noises most and men are usually worse affected than women.

If you go to this page http://www.exeterlaboratory.com/genetics/maternally-inherited-diabetes-and-deafness/ and click the "information sheet" button on the right, you can download a document which explains it quite simply.

 

[worcesterwoman]

Alternatively you may not have DNA related Mitochondrial disease with diabetes. I have one of the other types of Mitochondrial diabetes related to autosomal Mitochondrial disease, ie no inherited defect found (as yet).
So, be sure of which type of Mito you have before getting too caught up in ways of treating the diabetes.

 

[Dark Horse]

Alternatively you may not have DNA related Mitochondrial disease with diabetes. I have one of the other types of Mitochondrial diabetes related to autosomal Mitochondrial disease, ie no inherited defect found (as yet).
So, be sure of which type of Mito you have before getting too caught up in ways of treating the diabetes.

I think you are saying that you have mitochondrial disease due to a mutation in nuclear DNA rather than mitochondrial DNA. ( http://www.ncbi.nlm.nih.gov/books/NBK1224/ ) Thanks for adding that.