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Allergic to certain drugs

leviticus49

Newbie
Messages
3
Location
Barnsley South Yorkshire
Type of diabetes
Type 2
Treatment type
Tablets (oral)
Dislikes
Bigots, scabs & bossy women
I was diagnosed Diabetic around two years ago and started on 1 x Metformin per day. Over the next 18 months I was given Sitagliptin (in addition to 3 x Metformin) as the nurses/doctor was not happy with my blood sugar results. Eventually I was told to take two Met twice a day. Immediately I came out in a rash and intense itching. Managing to see a doctor after a week on this, I was advised to drop the Met to 3 a day. Same result. After another week, the Met was dropped altogether and put on Gliclazide. Still the same! I am now having to wait for almost two weeks to see a doctor about these drugs. I am ripping myself to pieces, my arms are like a toads skin, all knobbly, my neck, face and the back of my ears similar and my backside and small of the back are real mess according to my wife. Looking back to the start of treatment I have had tenderness and itching in the same areas but was told that this was probably due to the after effects of a bad Shingles attack. I fear not to take the meds but I cannot have this for the rest of my natch! Can anyone give me advice about this please?
 
@leviticus49 - Hello and Welcome to the Forum. I will tag @daisy1 who will provide you with some basic information. Have a good read and if you have any questions? Just ask - someone will come along and answer:)
Perhaps you could try taking Antihistamine tablets. Or if you have any Calamine Lotion apply this liberally to stop the itching. Or you could present yourself down at A & E.
 
I'm sorry to hear of the trouble you're having, I am allergic to some drugs and that's pretty much what happens to me. The itching is something to behold.

Only a medic can advise you, but making you wait two weeks when you might be having an allergic reaction seems somewhat excessive to me. What about the pharmacist that filled your prescription, are they available to talk to - and what do the leaflets inside the meds say - I would guess that it would be something like 'in the case of an allergic reaction, discontinue use' and it would outline what might constitute an allergic reaction.

Is there room within your diet to modify it to counter-balance stopping the meds? Shingles usually only affects one half of your body, as it follows the line of the infected nerve, so if this 'rash' crosses your centre-line, then it's not likely to be shingles.
 
@leviticus49

Hello and welcome to the forum :) As mentioned above, here is the basic information we give to new members and I hope you will find this useful. I do hope you will find a solution on here to your itching - I am sure some members will have had similar problems. Ask as many questions as you need to and someone will be able to help.

BASIC INFORMATION FOR NEW MEMBERS

Diabetes is the general term to describe people who have blood that is sweeter than normal. A number of different types of diabetes exist.

A diagnosis of diabetes tends to be a big shock for most of us. It’s far from the end of the world though and on this forum you’ll find over 150,000 people who are demonstrating this.

On the forum we have found that with the number of new people being diagnosed with diabetes each day, sometimes the NHS is not being able to give all the advice it would perhaps like to deliver - particularly with regards to people with type 2 diabetes.

The role of carbohydrate

Carbohydrates are a factor in diabetes because they ultimately break down into sugar (glucose) within our blood. We then need enough insulin to either convert the blood sugar into energy for our body, or to store the blood sugar as body fat.

If the amount of carbohydrate we take in is more than our body’s own (or injected) insulin can cope with, then our blood sugar will rise.

The bad news

Research indicates that raised blood sugar levels over a period of years can lead to organ damage, commonly referred to as diabetic complications.

The good news

People on the forum here have shown that there is plenty of opportunity to keep blood sugar levels from going too high. It’s a daily task but it’s within our reach and it’s well worth the effort.

Controlling your carbs

The info below is primarily aimed at people with type 2 diabetes, however, it may also be of benefit for other types of diabetes as well.
There are two approaches to controlling your carbs:

  • Reduce your carbohydrate intake
  • Choose ‘better’ carbohydrates

Reduce your carbohydrates

A large number of people on this forum have chosen to reduce the amount of carbohydrates they eat as they have found this to be an effective way of improving (lowering) their blood sugar levels.

The carbohydrates which tend to have the most pronounced effect on blood sugar levels tend to be starchy carbohydrates such as rice, pasta, bread, potatoes and similar root vegetables, flour based products (pastry, cakes, biscuits, battered food etc) and certain fruits.

Choosing better carbohydrates

Another option is to replace ‘white carbohydrates’ (such as white bread, white rice, white flour etc) with whole grain varieties. The idea behind having whole grain varieties is that the carbohydrates get broken down slower than the white varieties –and these are said to have a lower glycaemic index.
http://www.diabetes.co.uk/food/diabetes-and-whole-grains.html

The low glycaemic index diet is often favoured by healthcare professionals but some people with diabetes find that low GI does not help their blood sugar enough and may wish to cut out these foods altogether.

Read more on carbohydrates and diabetes

LOW CARB PROGRAM:
http://www.diabetes.co.uk/low carb program


Eating what works for you

Different people respond differently to different types of food. What works for one person may not work so well for another. The best way to see which foods are working for you is to test your blood sugar with a glucose meter.

To be able to see what effect a particular type of food or meal has on your blood sugar is to do a test before the meal and then test after the meal. A test 2 hours after the meal gives a good idea of how your body has reacted to the meal.

The blood sugar ranges recommended by NICE are as follows:

Blood glucose ranges for type 2 diabetes
  • Before meals: 4 to 7 mmol/l
  • 2 hours after meals: under 8.5 mmol/l
Blood glucose ranges for type 1 diabetes (adults)
  • Before meals: 4 to 7 mmol/l
  • 2 hours after meals: under 9 mmol/l
Blood glucose ranges for type 1 diabetes (children)
  • Before meals: 4 to 8 mmol/l
  • 2 hours after meals: under 10 mmol/l
However, those that are able to, may wish to keep blood sugar levels below the NICE after meal targets.

Access to blood glucose test strips

The NICE guidelines suggest that people newly diagnosed with type 2 diabetes should be offered:

  • structured education to every person and/or their carer at and around the time of diagnosis, with annual reinforcement and review
  • self-monitoring of plasma glucose to a person newly diagnosed with type 2 diabetes only as an integral part of his or her self-management education

Therefore both structured education and self-monitoring of blood glucose should be offered to people with type 2 diabetes. Read more on getting access to bloodglucose testing supplies.

You may also be interested to read questions to ask at a diabetic clinic

Note: This post has been edited from Sue/Ken's post to include up to date information.
 
Thank You for all the replies. I have tried Calomine lotion, no help! plus I looked like a escapee from a Halloween party. I have an appointment next Wednesday where I will ask for other treatments than the Metformin, Gliclazide and Sitagliptin I am on at the moment. Are there such things for people who are allergic to certain drugs?
 
It is unlikely that you are allergic to ALL the drugs you've been given, the only way to find out which (if any) is causing the rash is to stop one at a time (under your doctor's supervision) and see if the rash fades. Some people can develop allergy to a drug they have previously taken for a long time without problem. If you still have the rash after stopping metformin for a couple of weeks, that probably wasn't the cause - it could be the sitagliptin. Of course, it might be none of the drugs and you may have coincidentally developed an allergy to something else e.g. washing powder or shower gel!

Meanwhile, talk to your pharmacist about an over-the-counter hydrocortisone cream for the itching.
 
Each drug has the warning in it's patient notes that should a rash/hives or itching occur to let my doctor know immediately. Takes 11 days on average to get an appointment at our practice - hence my appointment next Wed. It is now almost 4 weeks since dropping the Metformin and starting on Gliclazide so it is possible that it is the Sitagliptin/Gliclazide thats causing my problem. Got hydrocortisome cream, does nothing! Antihistamine tablets also no reaction. Regarding Shingles, the pain/itching is on the same side and place as the initial outbreak, so could be a residual reaction (I'm told). My wife has used the same washing powder etc. for years and always makes sure my underclothes have no softener such as Comfort added. I will have to make my point clear when I do see the doc.
 
It could be you've developed an allergy to the "base" of the tablets, rather than the medication itself. Im sure that someone on the forum cant take stearate based meds, talk to a pharmacist asap as what it "just" hives at the moment could develope into something worse if you keep taking them
 
Regarding Shingles, the pain/itching is on the same side and place as the initial outbreak, so could be a residual reaction (I'm told).
Ah, I see, you've already had shingles. You could then be right, whenever I have an allergic reaction, sites of previous shingles become irritated as does the site of any previous allergic outburst. My GP called it something like anaphylactic memory - allergic reactions will re-ignite previous 'eruptions'.
 
Each drug has the warning in it's patient notes that should a rash/hives or itching occur to let my doctor know immediately. Takes 11 days on average to get an appointment at our practice - hence my appointment next Wed. It is now almost 4 weeks since dropping the Metformin and starting on Gliclazide so it is possible that it is the Sitagliptin/Gliclazide thats causing my problem. Got hydrocortisome cream, does nothing! Antihistamine tablets also no reaction. Regarding Shingles, the pain/itching is on the same side and place as the initial outbreak, so could be a residual reaction (I'm told). My wife has used the same washing powder etc. for years and always makes sure my underclothes have no softener such as Comfort added. I will have to make my point clear when I do see the doc.
The washing powder may not be a problem but having used it for years doesn't stop you from suddenly developing an allergy to it.
 
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