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<blockquote data-quote="eshobabu" data-source="post: 2325086" data-attributes="member: 531419"><p>I was going through my 6yr old daughter's test results - she was recently diagosed T1.</p><p></p><p>IA-2 Antibody: >120 H</p><p>Glt Decarbx Ab 11.2 IU/mL</p><p>IgA 193.0 mg/dL Normal</p><p>Anti-IgA Ab ELISA Normal</p><p>Insulin Ab (IAA) Normal</p><p>Gliadin IgA 20 Units Weak Positive (upto 19 normal)</p><p>Gliadin IgG 19 Units Normal</p><p>TTG IgA 4 U/mL Weak Positive</p><p></p><p></p><p>The GAD number is higher than range (0-5). IA-2 is quite high. Everything else is either normal or close to upper range of normal. I am reading conflicting pieces of research:</p><p>"IA2 antibodies have been shown to be a better marker of glycemic control and of a lower insulin requirement, indicating residual beta-cell function."</p><p></p><p>However, I have also read, "IAA prevalence correlates inversely with age at onset of diabetes; it is usually the first marker in young children at risk for diabetes [17] and found in approximately 70% of young children at time of diagnosis[1]." - I am assuming this is the Insulin AB that she tested normal for.</p><p></p><p>My daughter is 6, but I believe her diabetes is related to COVID - does anything stand out from these results? I have an appointment with our endo on Monday, what kind of questions should I ask on basis of test results above? At this time, she is using no basal (she went hypo even with 1 unit basal) and she needs between 0.5 to 1 unit of fast acting on basis of how many carbs she needs. If she runs for 20-30 minutes after food, she needs no insulin, so she is in a honeymoon phase right now.</p></blockquote><p></p>
[QUOTE="eshobabu, post: 2325086, member: 531419"] I was going through my 6yr old daughter's test results - she was recently diagosed T1. IA-2 Antibody: >120 H Glt Decarbx Ab 11.2 IU/mL IgA 193.0 mg/dL Normal Anti-IgA Ab ELISA Normal Insulin Ab (IAA) Normal Gliadin IgA 20 Units Weak Positive (upto 19 normal) Gliadin IgG 19 Units Normal TTG IgA 4 U/mL Weak Positive The GAD number is higher than range (0-5). IA-2 is quite high. Everything else is either normal or close to upper range of normal. I am reading conflicting pieces of research: "IA2 antibodies have been shown to be a better marker of glycemic control and of a lower insulin requirement, indicating residual beta-cell function." However, I have also read, "IAA prevalence correlates inversely with age at onset of diabetes; it is usually the first marker in young children at risk for diabetes [17] and found in approximately 70% of young children at time of diagnosis[1]." - I am assuming this is the Insulin AB that she tested normal for. My daughter is 6, but I believe her diabetes is related to COVID - does anything stand out from these results? I have an appointment with our endo on Monday, what kind of questions should I ask on basis of test results above? At this time, she is using no basal (she went hypo even with 1 unit basal) and she needs between 0.5 to 1 unit of fast acting on basis of how many carbs she needs. If she runs for 20-30 minutes after food, she needs no insulin, so she is in a honeymoon phase right now. [/QUOTE]
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