I was going through my 6yr old daughter's test results - she was recently diagosed T1.
IA-2 Antibody: >120 H
Glt Decarbx Ab 11.2 IU/mL
IgA 193.0 mg/dL Normal
Anti-IgA Ab ELISA Normal
Insulin Ab (IAA) Normal
Gliadin IgA 20 Units Weak Positive (upto 19 normal)
Gliadin IgG 19 Units Normal
TTG IgA 4 U/mL Weak Positive
The GAD number is higher than range (0-5). IA-2 is quite high. Everything else is either normal or close to upper range of normal. I am reading conflicting pieces of research:
"IA2 antibodies have been shown to be a better marker of glycemic control and of a lower insulin requirement, indicating residual beta-cell function."
However, I have also read, "IAA prevalence correlates inversely with age at onset of diabetes; it is usually the first marker in young children at risk for diabetes [17] and found in approximately 70% of young children at time of diagnosis[1]." - I am assuming this is the Insulin AB that she tested normal for.
My daughter is 6, but I believe her diabetes is related to COVID - does anything stand out from these results? I have an appointment with our endo on Monday, what kind of questions should I ask on basis of test results above? At this time, she is using no basal (she went hypo even with 1 unit basal) and she needs between 0.5 to 1 unit of fast acting on basis of how many carbs she needs. If she runs for 20-30 minutes after food, she needs no insulin, so she is in a honeymoon phase right now.
IA-2 Antibody: >120 H
Glt Decarbx Ab 11.2 IU/mL
IgA 193.0 mg/dL Normal
Anti-IgA Ab ELISA Normal
Insulin Ab (IAA) Normal
Gliadin IgA 20 Units Weak Positive (upto 19 normal)
Gliadin IgG 19 Units Normal
TTG IgA 4 U/mL Weak Positive
The GAD number is higher than range (0-5). IA-2 is quite high. Everything else is either normal or close to upper range of normal. I am reading conflicting pieces of research:
"IA2 antibodies have been shown to be a better marker of glycemic control and of a lower insulin requirement, indicating residual beta-cell function."
However, I have also read, "IAA prevalence correlates inversely with age at onset of diabetes; it is usually the first marker in young children at risk for diabetes [17] and found in approximately 70% of young children at time of diagnosis[1]." - I am assuming this is the Insulin AB that she tested normal for.
My daughter is 6, but I believe her diabetes is related to COVID - does anything stand out from these results? I have an appointment with our endo on Monday, what kind of questions should I ask on basis of test results above? At this time, she is using no basal (she went hypo even with 1 unit basal) and she needs between 0.5 to 1 unit of fast acting on basis of how many carbs she needs. If she runs for 20-30 minutes after food, she needs no insulin, so she is in a honeymoon phase right now.