Richard.E.Craig
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It remains unclear if ingested leucine has the same effect as leucine injected directly into the brain, he notes.
Dr. H. J. Roberts, M.D., F.A.C.P., F.C.C.P., internationally known medical consultant, researcher and world expert on aspartame, has declared aspartame disease to be a world epidemic. Dr. Roberts, who has authored many books on the subject, presented his findings at the First International Conference on Emerging Diseases (held in March l998 in Atlanta, Georgia), which was attended by doctors and scientists from 91 countries of the world.
Aspartame is made from two amino acids and methanol. When it is digested, it breaks down into these three parts. Amino acids are the normal breakdown products of proteins.
andAlthough all the sweeteners used in the EU have been approved and are deemed safe by the food safety authorities, internet forums, newspaper reports and some scientific literature continue to garner suspicion.
andIn response to the ERF’s reports the European Food Safety Authority’s (EFSA) panel on Food Additives and Nutrient Sources said there is no indication that aspartame causes cancer following its assessment of a study that linked regular intake of the sweetener with increased risk of certain cancers.
andWhile the results are promising for sweetener users, it is noted that the study was only based in Italy, and therefore generalisation to other populations is not possible. Additionally, the study was limited to only three types of cancer. Indeed, the earlier findings of the ERF study reported increased risk of leukaemia, lymphomas and breast cancer, none of which were considered by Bosetti and her co-workers.
andOn the other hand, a US study sponsored by the National Cancer Institute involving 285,079 men and 188,905 women, ages 50 to 69, found no statistically significant link between aspartame consumption and leukaemia, lymphomas or brain tumours (Cancer Epidemiol Biomarkers Prev. 2006, Vol. 15, pp. 1654-1659).
Furthermore, a review published in 2007 in Critical Reviews in Toxicology (Vol. 37, pp. 629-727) concluded that suggestions of adverse effects had 'no credible scientific basis'. The review was conduced by a panel of eight experts over an 11 month period. It considered over 500 studies, articles and reports conducted over the last 25 years - including work that was not published, but that was submitted to government bodies as part of the regulatory approvals process.
A team of national experts drawn from EU member states has concluded that there is no new evidence on aspartame that would require EFSA to reassess its opinion that the sweetener is safe, although additional studies could add to knowledge of the sweetener and its metabolites.
Although some studies have suggested possible adverse effects, the European Food Safety Authority (EFSA) has scrutinised the methodology and findings of safety studies and has repeatedly reaffirmed its positive safety opinion. The acceptable daily intake (ADI) is 40 mg/kg bw/day, and a 2002 opinion from the Scientific Committee on Food held that this level is unlikely to be exceeded.
They emphasized that using anecdotal data has great limitations and there is therefore a need for caution when interpreting them, but the said the information gathered could help guide the design of any investigative studies on sensitivity and possible underlying mechanisms.
In other words, dozens of studies have failed to find a relationship between the consumption of aspartame and long term health risks. While many people have reported adverse reactions to aspartame, most commonly headache, this has not been proven in research involving double blind trials looking at short term effects.
Despite this, it is possible that some people may have an unusual reaction and therefore might want to avoid consuming aspartame.
There is, in fact, one medically proven warning relating to the consumption of aspartame. It relates to one of the breakdown products of aspartame, an amino acid called phenylalanine.
Patients diagnosed with the rare hereditary disease Phenylketonuria should avoid aspartame as they have difficulty in metabolising phenylalanine, which accumulates and causes health problems.
Canderel is a brand of artificial sweetener made mainly from aspartame. Canderel is marketed by The Merisant Company, a global corporation with headquarters in Chicago, Illinois, also Switzerland, Mexico, and Australia.
Canderel was first marketed in France in 1979. The name "Canderel" is a combination of candi (or sugar cane) and airelles - the French word for bilberries.[1]
"Canderel granular" ingredients: maltodextrin, aspartame, acesulfame potassium, flavouring.
"Canderel tablets" ingredients: lactose, aspartame, acesulfame potassium, leucine, cross-linked CMC, flavouring.
Canderel is said to be interchangeable with sugar in a 1 to 10 mass ratio.[2
Conclusion
The Committee concluded that on the basis of its review of all the data in animals and
humans available to date, there is no evidence to suggest that there is a need to revise
the outcome of the earlier risk assessment or the ADI previously established for
aspartame.
You will then have no problems in publicly endorsing on behalf of Diabetes.co.uk that Aspartame is safe to consume and carries no risks to the diabetics who use it."Oh yes........just a small, well actually not very small addition........the Opinion of the Scientific Committee on Food: Update on the Safety of Aspartame (expressed on 4 December 2002). It hasn't changed........"
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