Thanks everybody for getting back on this with advice and experiences.
Looks like I'll be OK but must be extra careful with things.
I'm taking 2000mg of Metformin and 5mg Linagliptin per day to help manage diabetes.
I'll be getting into a more rigorous excersise pattern as well to help get the weight back down, thinking seriously of getting another decent bike very soon, I'm missing cycling the lanes and roads, so now I have good incentive.
Wonder if I've still got it in me