Then I don't understand why you seem to be lecturing us on post meal readings when you don't even know your own. Puzzling.I almost never take pre or post meal readings. Haven't done so since around 2017. But my 2 hour ogt is 10.9, JUST below the diabetic level, at the very top of the prediabetic range. I took it recently for the first time in 8/9 months. It is the nearest thing I have to a post meal reading.
I almost never take pre or post meal readings. Haven't done so since around 2017. But my 2 hour ogt is 10.9, JUST below the diabetic level, at the very top of the prediabetic range. I took it recently for the first time in 8/9 months. It is the nearest thing I have to a post meal reading.
But you’ve made a post and highlighted the risks of excessive readings at these times so why do you not take these? It seems illogical, at the very least, not to even do so as a monitoring sample taken occasionally or to establish levels for regular meals.I almost never take pre or post meal readings. Haven't done so since around 2017. But my 2 hour ogt is 10.9, JUST below the diabetic level, at the very top of the prediabetic range. I took it recently for the first time in 8/9 months. It is the nearest thing I have to a post meal reading.
GP -or rather she recommended I do the online one as they aren't doing them at the surgery during covid & I didn't want to go to the hospital for it.Hi,
Who conducted the recent OGT for you?
The OP discusses an ongoing time related event of beta cell death apparently caused by glucose levels being either too high or too low. This technique mentioned here is by definition a one shot measurement which references the last recorded FBG which could be over a year previous. it cannotbe used to support the hypothesis that low FBG kills beta cells.From the first link in Tannith's post:
"At the Mayo Clinic some of these difficulties are overcome. Autopsies are performed within 12 h of death (usually <6 h), including weekends. The Mayo Clinic integrated medical record system allows easy access to the prior clinical records of the cases. As the Mayo Clinic tends to be the primary health care provider for people hospitalized at the medical center for their final illness, most of the autopsy cases have had a general medical examination (including a fasting blood glucose) during the year before death.
In the present study, we took advantage of the unique autopsy material available at the Mayo Clinic to study 124 human pancreata from cases with and without diabetes and matched for obesity. All cases had a well-preserved pancreatic specimen and documented general medical exam, including a fasting blood glucose obtained during the 12 months before death."
The FBG reading is directly affected by liver dump / dawn phenomenon, and is also influeced by meals and snacks eaten the previous day, so is no longer used for diagnosis. The HbA1c is the gold standard used now in favour over the FBG.But you’ve made a post and highlighted the risks of excessive readings at these times so why do you not take these? It seems illogical, at the very least, not to even do so as a monitoring sample taken occasionally or to establish levels for regular meals.
How about hba1c as these are also used as a measure of risk of complications?
Why only use fbg, which whilst it has its merits also has limitations for interpretation of the overall picture?
Exactly my point. Relying on solely a fbg misses so much extra information that is readily available in hba1c and pre and post meal readings. @Tannith seems to have chosen to ignore my post so we won’t know why these have been omittedThe FBG reading is directly affected by liver dump / dawn phenomenon, and is also influeced by meals and snacks eaten the previous day, so is no longer used for diagnosis. The HbA1c is the gold standard used now in favour over the FBG.
Try this hardcopyThat link doesn't work (for me anyway). Though it might just be my browser.
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Thanks very much. Very interesting.Try this hardcopy
Its probably in the wrong place, so apologies to the Op for possible derailment. It was an en passant comment.Thanks very much. Very interesting.
It makes me wonder who the participants were, age, type of diabetes, general health and health care.Don;t believe everything you read . I have just uncovered a study of 3,000 inpateints in an USA hospital who registered a hypo event of 3.9 mmol/l or less (70mmg.dl) and in the follow up part of the study 33% of them had died in the 6 month period. I think this says more about the standard of care rsther than dabetes alone. The conclusion they drew was that hypo's are generally fatal events.
And why were they inpatients?It makes me wonder who the participants were, age, type of diabetes, general health and health care.
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