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Can insulin be formed again in type 1 diabetes
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<blockquote data-quote="Hoping4Cure" data-source="post: 1465069" data-attributes="member: 393050"><p>Incorrect. You're asserting things which are simply untrue. You have no evidence on which to base this assertion, and there is plenty of evidence that the opposite is true.</p><p></p><p>Do you know what neogenesis is? Hint: it happens in every human being's body, continuously. Otherwise we could not live. Beta cells included. They continuously grow and replicate, then are killed off for the most part, but if you reduce or halt auto-immunity beta cells will grow back on their own.</p><p></p><p>My own c-peptide levels have <em>risen </em>in the past two years, so yes, you're absolutely wrong.</p><p></p><p>Please, don't make confident assertions that regenerating beta cells or reversing type 1 diabetes is "virtually impossible", because that's not what the current research shows. You're going by ideas from the 90s that once beta cells are destroyed there are none coming back to take their place, whereas this would preclude c-peptide levels rising.</p><p></p><p>I had undetectable levels of c-peptide back in 2011 and now have 0.107 nmol / L (last I checked). That's 0.33 ng/ml if I remember the converted value correctly. Nearly a third of what a non-diabetic's fasting c-peptides are, on average. That's not nothing, and a big improvement over my previous undetectable levels.</p><p></p><p>Please, don't spread unsubstantiated opinion as fact, or blatant falsehoods.</p><p></p><p>There are several type 1 diabetics besides myself who have managed to increase their c-peptide levels significantly, at least temporarily. Yes, many of us saw rises and then lowering, but the fact that we've seen rises in lab-verified c-peptide tests, is incontrovertible proof that what you're asserting is false.</p><p></p><p><a href="https://groups.google.com/forum/#!topic/curetype1/-Q8CeZbDqpk%5B1-25%5D" target="_blank">https://groups.google.com/forum/#!topic/curetype1/-Q8CeZbDqpk[1-25]</a></p><p></p><p>Unless you think several people falsified lab test results from different labs and hospitals in order to trick you?</p><p></p><p>If you boost c-peptide levels, however that may occur, you've boosted functional beta cells which produce insulin in response to elevated blood sugar. That means mature beta cells can not only survive but replicate and regenerate.</p><p></p><p>Read this to educate yourself about the lifespan of cells:</p><p></p><p><a href="https://www.medicalsciencenavigator.com/physiology-of-self-renewal/" target="_blank">https://www.medicalsciencenavigator.com/physiology-of-self-renewal/</a></p><p></p><p>"Only a few body parts last most of your lifetime. They are the neurons of the cerebral cortex, the inner lens cells of the eye, and muscle cells of the heart."</p><p></p><p>Ask yourself this simple question: if functional beta cells are often found in the pancreases of deceased type 1 diabetics who've lived many decades, and nearly all body cell types die off to be recycled and then renewed, what does that imply?</p><p></p><p>It implies that the beta cells which are found during autopsy weren't created prior to type 1 diagnosis, but rather are recently replicated and/or regenerated. This is just common sense.</p></blockquote><p></p>
[QUOTE="Hoping4Cure, post: 1465069, member: 393050"] Incorrect. You're asserting things which are simply untrue. You have no evidence on which to base this assertion, and there is plenty of evidence that the opposite is true. Do you know what neogenesis is? Hint: it happens in every human being's body, continuously. Otherwise we could not live. Beta cells included. They continuously grow and replicate, then are killed off for the most part, but if you reduce or halt auto-immunity beta cells will grow back on their own. My own c-peptide levels have [I]risen [/I]in the past two years, so yes, you're absolutely wrong. Please, don't make confident assertions that regenerating beta cells or reversing type 1 diabetes is "virtually impossible", because that's not what the current research shows. You're going by ideas from the 90s that once beta cells are destroyed there are none coming back to take their place, whereas this would preclude c-peptide levels rising. I had undetectable levels of c-peptide back in 2011 and now have 0.107 nmol / L (last I checked). That's 0.33 ng/ml if I remember the converted value correctly. Nearly a third of what a non-diabetic's fasting c-peptides are, on average. That's not nothing, and a big improvement over my previous undetectable levels. Please, don't spread unsubstantiated opinion as fact, or blatant falsehoods. There are several type 1 diabetics besides myself who have managed to increase their c-peptide levels significantly, at least temporarily. Yes, many of us saw rises and then lowering, but the fact that we've seen rises in lab-verified c-peptide tests, is incontrovertible proof that what you're asserting is false. [URL='https://groups.google.com/forum/#!topic/curetype1/-Q8CeZbDqpk%5B1-25%5D']https://groups.google.com/forum/#!topic/curetype1/-Q8CeZbDqpk[1-25][/URL] Unless you think several people falsified lab test results from different labs and hospitals in order to trick you? If you boost c-peptide levels, however that may occur, you've boosted functional beta cells which produce insulin in response to elevated blood sugar. That means mature beta cells can not only survive but replicate and regenerate. Read this to educate yourself about the lifespan of cells: [URL]https://www.medicalsciencenavigator.com/physiology-of-self-renewal/[/URL] "Only a few body parts last most of your lifetime. They are the neurons of the cerebral cortex, the inner lens cells of the eye, and muscle cells of the heart." Ask yourself this simple question: if functional beta cells are often found in the pancreases of deceased type 1 diabetics who've lived many decades, and nearly all body cell types die off to be recycled and then renewed, what does that imply? It implies that the beta cells which are found during autopsy weren't created prior to type 1 diagnosis, but rather are recently replicated and/or regenerated. This is just common sense. [/QUOTE]
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