It is a generalisation of course.
However I think primarily there is variability on the extent to which we're insulin resistant/sensitive but given that, then one can make a food choice based on the dietary paradigm adopted and one criterion may be the glycaemic load.
Assuming someone chooses low carb then as a general statement a portion of a food containing 7 spoonful equivalents of sugar is likely to affect them more than on containing 1 spoonful.
But there are then no doubt nuances such as - but not limited to - which microbes occupy our gut and how that affects us differently.